CRISP3, Polyclonal Antibody

Aeg2; CRS3; SGP28; CRISP-3; dJ442L6.3

For Research Use Only. Not for use in diagnostic procedures.

Polyclonal

IgG

Rabbit

Antigen affinity purification

1.6mg/mL (lot specific)

Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.

Manufactured in an ISO 9001:2015 Certified Laboratory.

Small volumes of anti-CRISP3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Cysteine-rich secretory proteins (CRISPs) represent a family of evolutionarily conserved proteins which may play a role in the innate immune system and are transcriptionally regulated by androgens in several tissues. AEG is a sperm surface protein involved in the fusion of egg and sperm. Although CRISP-1 (also designated AEG-like protein, ARP, cysteine-rich secretory protein-1 or AEG-related protein) is not the ortholog of rodent AEG, it resembles AEG in that it is an epididymal secretory glycoprotein that binds to the postacrosomal region of the sperm head. CRISP-1 coats the postacrosomal region of sperm heads as they pass through the epididymis. CRISP-1 is found in all regions of the epididymis, ductus deferens, seminal plasma and sperm. CRISP-3 is expressed in pancreas and prostate tissues and, along with CRISP-1, is expressed in saliva.

ELISA (EIA), Immunohistochemistry (IHC)

IHC: 1:50-1:200

Immunohistochemistry of paraffin-embedded Human colon cancer tissue using CRISP3 Polyclonal Antibody at dilution 1:40

Immunohistochemistry of paraffin-embedded Human liver cancer tissue using CRISP3 Polyclonal Antibody at dilution 1:40

30,116 Da

cysteine-rich secretory protein 3

cysteine-rich secretory protein 3; cysteine-rich secretory protein-3; specific granule protein (28 kDa); specific granule protein of 28 kDa

Cysteine-rich secretory protein 3

CRISP-3; SGP28  [Similar Products]

CRIS3_HUMAN

CRISP3: Belongs to the CRISP family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 6p12.3

Cellular Component: proteinaceous extracellular matrix; extracellular space; specific granule; extracellular region

Biological Process: innate immune response; defense response

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