Homeobox B13, Polyclonal Antibody

homeobox B13; HOXB13; PSGD; homeo box B13; homeobox B13 antibody; HOXB13 antibody; PSGD antibody; homeo box B13 antibody; Homeobox B13; Homeobox B13

For Research Use Only. Not for use in diagnostic procedures.

Polyclonal

Goat

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

100ug specific antibody in 200ul (lot specific)

Aliquot and store at -20 degree C. Minimize freezing and thawing.

Manufactured in an ISO 9001:2008 Certified Laboratory.

Small volumes of anti-HOXB13 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Peptide ELISA (EIA), Western Blot (WB)

Peptide ELISA: Antibody detection limit dilution 1: 128000.
Western Blot: Approx 28kDa band observed in lysates of cell lines A431 and HeLa (calculated MW of 30.7kDa according to NP_006352.2). Recommended concentration: 0.1-0.3ug/ml.

(0.1ug/ml) staining of HeLa cell lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

30,676 Da

homeobox B13

homeobox protein Hox-B13

Homeobox protein Hox-B13

HXB13_HUMAN

This gene encodes a transcription factor that belongs to the homeobox gene family. Genes of this family are highly conserved among vertebrates and essential for vertebrate embryonic development. This gene has been implicated to play a role in fetal skin development and cutaneous regeneration. In mice, a similar gene was shown to exhibit temporal and spatial colinearity in the main body axis of the embryo, but was not expressed in the secondary axes, which suggests functions in body patterning along the axis. This gene and other HOXB genes form a gene cluster at chromosome the 17q21-22 region. [provided by RefSeq, Jul 2008]

HOXB13: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family.

Protein type: Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: 17q21.2

Cellular Component: nucleoplasm; transcription factor complex

Molecular Function: sequence-specific DNA binding

Biological Process: angiogenesis; epidermis development; regulation of growth; regulation of transcription, DNA-dependent; response to testosterone stimulus; response to wounding; transcription, DNA-dependent

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