Product Name
TROY/TAJ, Polyclonal Antibody
Full Product Name
TROY / TAJ Antibody
Product Synonym Names
TAJ alpha; TAJ; TNFRSF 19; TRADE; Tnfrsf19; AL023044; AW123854; TRADE; Tnfrsf20; Troy
Product Gene Name
anti-TROY/TAJ antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q9JLL3
Purity/Purification
Affinity purified
Form/Format
100 ug (0.5 mg/ml) rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Appearance: Colorless liquid
Concentration
0.5 mg/ml (lot specific)
Immunogen
Synthetic peptide mapping to the C-terminus of mouse TROY
Handling
The antibody solution should be gently mixed before use.
Preparation and Storage
At -20 degree C
Shelf Life: 12 months
Other Notes
Small volumes of anti-TROY/TAJ antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-TROY/TAJ antibody
Background: TROY (also designated TAJ), a member of the TNFR superfamily, exists as several isoforms that vary in functions. Full length TROY contains a cytoplasmic tail, which recruits tumor necrosis factor receptor-associated factor (TRAF) 2. The interaction between TROY and TRAF2 promotes cell survival thromugh the NFkappaB signaling pathway. One truncated version of TROY, designated TNFRSF19, contains a shortened cytoplasmic tail, which prevents TNFRSF19 from activating the NFkappaB signal transduction pathway.
Applications Tested/Suitable for anti-TROY/TAJ antibody
Western Blot (WB)
Application Notes for anti-TROY/TAJ antibody
Western blotting (1-4 ug/ml). However, the optimal concentrations should be determined individually. The antibody recognizes mouse TROY. Reactivity to other species has not been tested.
Testing Data of anti-TROY/TAJ antibody
NCBI/Uniprot data below describe general gene information for TROY/TAJ. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001157627.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001164155.1
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UniProt Primary Accession #
Q9JLL3
[Other Products]
UniProt Secondary Accession #
Q80T13; Q812G3; Q9JHF1; Q9JJH6; Q9JLL2; Q9QXW7[Other Products]
UniProt Related Accession #
Q9JLL3[Other Products]
Molecular Weight
38,471 Da
NCBI Official Full Name
tumor necrosis factor receptor superfamily member 19
NCBI Official Synonym Full Names
tumor necrosis factor receptor superfamily, member 19
NCBI Official Symbol
Tnfrsf19 [Similar Products]
NCBI Official Synonym Symbols
TAJ; Troy; TRADE; AL023044; AW123854; TAJ-ALPHA
[Similar Products]
NCBI Protein Information
tumor necrosis factor receptor superfamily member 19
UniProt Protein Name
Tumor necrosis factor receptor superfamily member 19
UniProt Synonym Protein Names
TRADE; Toxicity and JNK inducer
UniProt Gene Name
Tnfrsf19 [Similar Products]
UniProt Synonym Gene Names
Taj; Troy [Similar Products]
UniProt Entry Name
TNR19_MOUSE
UniProt Comments for TROY/TAJ
TNFRSF19: Can mediate activation of JNK and NF-kappa-B. May promote caspase-independent cell death. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral
Cellular Component: membrane; plasma membrane; extracellular region; integral to membrane
Biological Process: positive regulation of I-kappaB kinase/NF-kappaB cascade; hair follicle development
Research Articles on TROY/TAJ
1. TROY negatively modulates remyelination in the central nervous system.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
