Product Name
WIF1, cDNA Clone
Popular Item
Full Product Name
WIF1 cDNA Clone
Product Gene Name
WIF1 cdna clone
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atggcccgga ggagcgcctt ccctgccgcc gcgctctggc tctggagcat cctcctgtgc ctgctggcac tgcgggcgga ggccgggccg ccgcaggagg agagcctgta cctatggatc gatgctcacc aggcaagagt actcatagga tttgaagaag atatcctgat tgtttcggag gggaaaatgg caccttttac acatgatttc agaaaagcgc aacagagaat gccagctatt cctgtcaata tccattccat gaattttacc tggcaagctg cagggcaggc agaatacttc tatgaattcc tgtccttgcg ctccctggat aaaggcatca tggcagatcc aaccgtcaat gtccctctgc tgggaacagt gcctcacaag gcatcagttg ttcaagttgg tttcccatgt cttggaaaac aggatggggt ggcagcattt gaagtggatg tgattgttat gaattctgaa ggcaacacca ttctcaaaac acctcaaaat gctatcttct ttaaaacatg tcaacaagct gagtgcccag gcgggtgccg aaatggaggc ttttgtaatg aaagacgcat ctgcgagtgt cctgatgggt tccacggacc tcactgtgag aaagcccttt gtaccccacg atgtatgaat ggtggacttt gtgtgactcc tggtttctgc atctgcccac ctggattcta tggagtgaac tgtgacaaag caaactgctc aaccacctgc tttaatggag ggacctgttt ctaccctgga aaatgtattt gccctccagg actagaggga gagcagtgtg aaatcagcaa atgcccacaa ccctgtcgaa atggaggtaa atgcattggt aaaagcaaat gtaagtgttc caaaggttac cagggagacc tctgttcaaa gcctgtctgc gagcctggct gtggtgcaca tggaacctgc catgaaccca acaaatgcca atgtcaagaa ggttggcatg gaagacactg caataaaagg tacgaagcca gcctcataca tgccctgagg ccagcaggcg cccagctcag gcagcacacg ccttcactta aaaaggccga ggagcggcgg gatccacctg aatccaatta catctggtga
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of WIF1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for WIF1. It may not necessarily be applicable to this product.
NCBI Accession #
BC018037
[Other Products]
UniProt Secondary Accession #
Q6UXI1; Q8WVG4[Other Products]
UniProt Related Accession #
Q9Y5W5[Other Products]
Molecular Weight
41,528 Da
NCBI Official Full Name
Homo sapiens WNT inhibitory factor 1, mRNA
NCBI Official Synonym Full Names
WNT inhibitory factor 1
NCBI Official Symbol
WIF1 [Similar Products]
NCBI Official Synonym Symbols
WIF-1
[Similar Products]
NCBI Protein Information
wnt inhibitory factor 1
UniProt Protein Name
Wnt inhibitory factor 1
Protein Family
Wnt inhibitory factor
UniProt Gene Name
WIF1 [Similar Products]
UniProt Synonym Gene Names
WIF-1 [Similar Products]
UniProt Entry Name
WIF1_HUMAN
NCBI Summary for WIF1
The protein encoded by this gene functions to inhibit WNT proteins, which are extracellular signaling molecules that play a role in embryonic development. This protein contains a WNT inhibitory factor (WIF) domain and five epidermal growth factor (EGF)-like domains, and is thought to be involved in mesoderm segmentation. This gene functions as a tumor suppressor gene, and has been found to be epigenetically silenced in various cancers. [provided by RefSeq, Jun 2010]
UniProt Comments for WIF1
WIF1: Binds to WNT proteins and inhibits their activities. May be involved in mesoderm segmentation.
Protein type: Secreted, signal peptide; Secreted; Inhibitor
Chromosomal Location of Human Ortholog: 12q14.3
Molecular Function: protein binding
Research Articles on WIF1
1. Results provide evidence that WIF1 is frequently methylated in oral squamous cell carcinoma (OSCC), but not in oral submucous fibrosis tissues, which results in reduced expression. This epigenetic biomarker can be used for the early detection of OSCC.
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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