Full Product Name
KRT85 Antibody - N-terminal region
Product Gene Name
anti-KRT85 antibody
[Similar Products]
Product Synonym Gene Name
HB5; Hb-5; KRTHB5; hHb5[Similar Products]
Antibody/Peptide Pairs
KRT85 peptide (MBS3241991) is used for blocking the activity of KRT85 antibody (MBS3217092)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Synthetic peptide located within the following region: CGPSPPCITT VSVNESLLTP LNLEIDPNAQ CVKQEEKEQI KSLNSRFAAF
3D Structure
ModBase 3D Structure for P78386
Species Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Sheep
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Homology
Cow: 92%; Dog: 86%; Guinea Pig: 86%; Horse: 92%; Human: 100%; Mouse: 86%; Pig: 93%; Rabbit: 86%; Rat: 86%; Sheep: 92%
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human KRT85
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-KRT85 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-KRT85 antibody
This is a rabbit polyclonal antibody against KRT85. It was validated on Western Blot
Target Description: The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5.
Product Categories/Family for anti-KRT85 antibody
Polyclonal; Various;
Applications Tested/Suitable for anti-KRT85 antibody
Western Blot (WB)
Western Blot (WB) of anti-KRT85 antibody
WB Suggested Anti-KRT85 Antibody
Titration: 1.0 ug/ml
Positive Control: OVCAR-3 Whole CellKRT85 is supported by BioGPS gene expression data to be expressed in OVCAR3
NCBI/Uniprot data below describe general gene information for KRT85. It may not necessarily be applicable to this product.
NCBI Accession #
NP_002274
[Other Products]
NCBI GenBank Nucleotide #
NM_002283
[Other Products]
UniProt Primary Accession #
P78386
[Other Products]
UniProt Related Accession #
P78386[Other Products]
NCBI Official Full Name
keratin, type II cuticular Hb5 isoform 1
NCBI Official Synonym Full Names
keratin 85
NCBI Official Symbol
KRT85 [Similar Products]
NCBI Official Synonym Symbols
HB5; K85; Hb-5; hHb5; ECTD4; KRTHB5
[Similar Products]
NCBI Protein Information
keratin, type II cuticular Hb5
UniProt Protein Name
Keratin, type II cuticular Hb5
UniProt Synonym Protein Names
Hair keratin K2.12; Keratin-85; K85; Type II hair keratin Hb5; Type-II keratin Kb25
UniProt Gene Name
KRT85 [Similar Products]
UniProt Synonym Gene Names
KRTHB5; K85 [Similar Products]
UniProt Entry Name
KRT85_HUMAN
NCBI Summary for KRT85
The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. [provided by RefSeq, Jul 2008]
Research Articles on KRT85
1. Our study confirms linkage of a variant clinical form of hair-nail ectodermal dysplasia to chromosome 12 without any mutation in the coding sequences of the KRTHB5 gene.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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