Full Product Name
RBM25 Antibody - middle region
Product Gene Name
anti-RBM25 antibody
[Similar Products]
Product Synonym Gene Name
S164; NET52; RNPC7; Snu71; RED120; fSAP94[Similar Products]
Antibody/Peptide Pairs
RBM25 peptide (MBS3244685) is used for blocking the activity of RBM25 antibody (MBS3219823)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Synthetic peptide located within the following region: DRDRTKERDR DRDRERDRDR DRERSSDRNK DRSRSREKSR DRERERERER
3D Structure
ModBase 3D Structure for P49756
Purity/Purification
Affinity purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human RBM25
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-RBM25 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-RBM25 antibody
RNA-binding protein that acts as a regulator of alternative pre-mRNA splicing. Involved in apoptotic cell death through the regulation of the apoptotic factor BCL2L1 isoform expression. Modulates the ratio of proapoptotic BCL2L1 isoform S to antiapoptotic BCL2L1 isoform L mRNA expression. When overexpressed, stimulates proapoptotic BCL2L1 isoform S 5'-splice site (5'-ss) selection, whereas its depletion caused the accumulation of antiapoptotic BCL2L1 isoform L. Promotes BCL2L1 isoform S 5'-ss usage through the 5'-CGGGCA-3' RNA sequence. Its association with LUC7L3 promotes U1 snRNP binding to a weak 5' ss in a 5'-CGGGCA-3'-dependent manner. Binds to the exonic splicing enhancer 5'-CGGGCA-3' RNA sequence located within exon 2 of the BCL2L1 pre-mRNA. Also involved in the generation of an abnormal and truncated splice form of SCN5A in heart failure.
Product Categories/Family for anti-RBM25 antibody
Polyclonal; RNA Binding Proteins; Apoptosis;
Applications Tested/Suitable for anti-RBM25 antibody
Western Blot (WB)
Western Blot (WB) of anti-RBM25 antibody
Host: Rabbit
Target Name: RBM25
Sample Tissue: Human HT1080 Whole Cell lysates
Antibody Dilution: 1ug/ml
NCBI/Uniprot data below describe general gene information for RBM25. It may not necessarily be applicable to this product.
NCBI Accession #
NP_067062.1
[Other Products]
NCBI GenBank Nucleotide #
NM_021239.2
[Other Products]
UniProt Primary Accession #
P49756
[Other Products]
UniProt Related Accession #
P49756[Other Products]
NCBI Official Full Name
RNA-binding protein 25
NCBI Official Synonym Full Names
RNA binding motif protein 25
NCBI Official Symbol
RBM25 [Similar Products]
NCBI Official Synonym Symbols
S164; NET52; RNPC7; Snu71; RED120; fSAP94
[Similar Products]
NCBI Protein Information
RNA-binding protein 25
UniProt Protein Name
RNA-binding protein 25
UniProt Synonym Protein Names
Arg/Glu/Asp-rich protein of 120 kDa; RED120; Protein S164; RNA-binding motif protein 25; RNA-binding region-containing protein 7
Protein Family
RNA-binding protein
UniProt Gene Name
RBM25 [Similar Products]
UniProt Synonym Gene Names
RNPC7 [Similar Products]
UniProt Entry Name
RBM25_HUMAN
Research Articles on RBM25
1. controls the splicing of key genes, including those encoding the apoptotic regulator BCL-X and the MYC inhibitor BIN1
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
