Full Product Name
D3DR Polyclonal Antibody
Product Gene Name
anti-D3DR antibody
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P35462
Other Notes
Small volumes of anti-D3DR antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for D3DR. It may not necessarily be applicable to this product.
NCBI Accession #
NP_000787.2
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NCBI GenBank Nucleotide #
NM_000796.5
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UniProt Primary Accession #
P35462
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UniProt Secondary Accession #
Q4VBM8; A1A4V5[Other Products]
UniProt Related Accession #
P35462[Other Products]
Molecular Weight
40,760 Da
NCBI Official Full Name
D(3) dopamine receptor isoform a
NCBI Official Synonym Full Names
dopamine receptor D3
NCBI Official Symbol
DRD3 [Similar Products]
NCBI Official Synonym Symbols
D3DR; ETM1; FET1
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NCBI Protein Information
D(3) dopamine receptor
UniProt Protein Name
D(3) dopamine receptor
UniProt Synonym Protein Names
Dopamine D3 receptor
UniProt Gene Name
DRD3 [Similar Products]
NCBI Summary for D3DR
This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD). [provided by RefSeq, Jul 2008]
UniProt Comments for D3DR
Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Promotes cell proliferation.
Research Articles on D3DR
1. This study adds to the growing evidence on the association of single- and multiple-risk variants in DRD3, DRD4, and FEV with aggressive behavior in Chinese adolescents.
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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