Product Name
BACH2, Blocking Peptide
Full Product Name
BACH2 Antibody (C-term) Blocking peptide
Product Synonym Names
Transcription regulator protein BACH2; BTB and CNC homolog 2; BACH2
Product Gene Name
BACH2 blocking peptide
[Similar Products]
Antibody/Peptide Pairs
BACH2 peptide (MBS9217436) is used for blocking the activity of BACH2 antibody (MBS9203899)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q9BYV9
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Cellular Location
Cytoplasm. Nucleus. Note: Nucleocytoplasmic shuttling is controlled by phosphorylation
Tissue Location
B-cell specific.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Other Notes
Small volumes of BACH2 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
BACH2 blocking peptide
Transcriptional regulator that acts as repressor or activator. Binds to Maf recognition elements (MARE). Play important roles in coordinating transcription activation and repression by MAFK (By similarity). Induces apoptosis in response to oxidative stress through repression of the antiapoptotic factor HMOX1.
NCBI/Uniprot data below describe general gene information for BACH2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001164265.1
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NCBI GenBank Nucleotide #
NM_001170794.1
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UniProt Primary Accession #
Q9BYV9
[Other Products]
UniProt Secondary Accession #
Q59H70; Q5T793; Q9NTS5; E1P518[Other Products]
UniProt Related Accession #
Q9BYV9[Other Products]
Molecular Weight
92,537 Da
NCBI Official Full Name
transcription regulator protein BACH2
NCBI Official Synonym Full Names
BTB domain and CNC homolog 2
NCBI Official Symbol
BACH2 [Similar Products]
NCBI Official Synonym Symbols
BTBD25
[Similar Products]
NCBI Protein Information
transcription regulator protein BACH2
UniProt Protein Name
Transcription regulator protein BACH2
UniProt Synonym Protein Names
BTB and CNC homolog 2
Protein Family
Transcription regulator protein
UniProt Gene Name
BACH2 [Similar Products]
UniProt Entry Name
BACH2_HUMAN
UniProt Comments for BACH2
BACH2: Transcriptional regulator that acts as repressor or activator. Binds to Maf recognition elements (MARE). Play important roles in coordinating transcription activation and repression by MAFK. Belongs to the bZIP family. CNC subfamily.
Protein type: DNA-binding; Transcription factor
Chromosomal Location of Human Ortholog: 6q15
Cellular Component: nucleus
Molecular Function: transcription factor activity; ubiquitin-protein ligase activity
Biological Process: transcription from RNA polymerase II promoter
Research Articles on BACH2
1. The study identifies a strong association of Coeliac Disease with a network of BACH2 regulated genes, supporting emerging evidence of an important role of BACH2 in the regulation of T cell differentiation and prevention of autoimmune disease.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
