Solute Carrier Family 22 Member 5 (SLC22A5), ELISA Kit

For Research Use Only. Not for use in diagnostic procedures.

Store all reagents at 2-8 degree C

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.

Small volumes of SLC22A5 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9348455 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Solute Carrier Family 22 Member 5 (SLC22A5) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing SLC22A5. The ELISA analytical biochemical technique of the MBS9348455 kit is based on SLC22A5 antibody-SLC22A5 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect SLC22A5 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, SLC22A5. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

62,567 Da

solute carrier family 22 member 5

solute carrier family 22 member 5

Solute carrier family 22 member 5

Octn2  [Similar Products]

S22A5_RAT

mediates high-affinity sodium-dependent carnitine transport and sodium-independent organic cation transport [RGD, Feb 2006]

SLC22A5: Sodium-ion dependent, high affinity carnitine transporter. Involved in the active cellular uptake of carnitine. Transports one sodium ion with one molecule of carnitine. Also transports organic cations such as tetraethylammonium (TEA) without the involvement of sodium. Also relative uptake activity ratio of carnitine to TEA is 11.3. Defects in SLC22A5 are the cause of systemic primary carnitine deficiency (CDSP). CDSP is an autosomal recessive disorder of fatty acid oxidation caused by defective carnitine transport. Present early in life with hypoketotic hypoglycemia and acute metabolic decompensation, or later in life with skeletal myopathy or cardiomyopathy. Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Transporter; Membrane protein, integral; Transporter, SLC family; Membrane protein, multi-pass

Cellular Component: apical plasma membrane; basolateral plasma membrane; brush border membrane; integral to membrane; integral to plasma membrane; mitochondrion

Molecular Function: antibiotic transporter activity; ATP binding; carnitine transporter activity; cation:cation antiporter activity; PDZ domain binding; protein binding; quaternary ammonium group transmembrane transporter activity; symporter activity; transmembrane transporter activity

Biological Process: ***** heart development; antibiotic transport; carnitine metabolic process; carnitine transport; locomotory behavior; mitochondrion organization and biogenesis; quaternary ammonium group transport; quorum sensing during interaction with host; reproductive structure development; sodium ion transport; transmembrane transport; triacylglycerol metabolic process

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.