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Phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE), Polyclonal Antibody

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产品名称: Phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE), Polyclonal Antibody
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简单介绍

Phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE), Polyclonal Antibody


Phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE), Polyclonal Antibody  的详细介绍
Product Name

Phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE), Polyclonal Antibody

Full Product Name

Polyclonal Antibody to Phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE)

Product Gene Name

anti-PIKFYVE antibody

[Similar Products]
Matching Pairs
Unconjugated Antibody: Phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE) (MBS2006869)
Immunogen: Phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE) (MBS2010940)
Matching Pairs
Unconjugated Antibody: Phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE) (MBS2006869)
APC-CY7 Conjugated Antibody: Phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE) (MBS2082942)
Matching Pairs
Unconjugated Antibody: Phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE) (MBS2006869)
PE Conjugated Antibody: Phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE) (MBS2082943)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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Immunogen Sequence
Antigen: The target protein is fused with two N-terminal Tags, His-tag and its sequence is listed below.
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGS-T NRTVEAEPQP TKKASGMLSF FRGTAGKSPD LSSQKRETLR GADSAYYQVG QAGKEGLESQ GLEPQDEVDG GDTQKKQLTN PHVELQFSDA NAKFYCRLYY AGEFHKMREV ILGSSEEEFI RSLSHSSPWQ ARGGKSGAAF YATEDDRFIL KQMPRLEVQS FLDFAPHYFN YITNAVQQKR PTALAKILGV YRIGYKNSQN NTEKKLDLLV MENLFYGRKM AQVFDLKGSL RNRNVKTDTG KESCDVVLLD E
3D Structure
ModBase 3D Structure for Q9Z1T6
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Mouse
Specificity
The antibody is a rabbit polyclonal antibody raised against PIKFYVE. It has been selected for its ability to recognize PIKFYVE in immunohistochemical staining andwestern blotting.
Purity/Purification
Affinity Chromatography
Form/Format
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.
Concentration
200ug/ml (lot specific)
Immunogen
Recombinant PIKFYVE (Thr1680~Glu1931) expressed in E.coli.
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2082944
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Other Notes
Small volumes of anti-PIKFYVE antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Applications Tested/Suitable for anti-PIKFYVE antibody
Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB)
Application Notes for anti-PIKFYVE antibody
Western blotting: 1:100-400
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200

Western Blot (WB) of anti-PIKFYVE antibody
Western Blot: Sample: Recombinant protein.
anti-PIKFYVE antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-PIKFYVE antibody
DABstainingonIHC-P.Samples:MouseTissue)
anti-PIKFYVE antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for PIKFYVE. It may not necessarily be applicable to this product.
NCBI GI #
890828233
NCBI GeneID
18711
NCBI Accession #
NP_001297553.1 [Other Products]
NCBI GenBank Nucleotide #
NM_001310624.1 [Other Products]
UniProt Primary Accession #
Q9Z1T6 [Other Products]
UniProt Secondary Accession #
Q3TNE4; Q3UTT6; Q69ZU1; Q9CU94; E9QL40[Other Products]
UniProt Related Accession #
Q9Z1T6[Other Products]
Molecular Weight
55,999 Da
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NCBI Official Full Name
1-phosphatidylinositol 3-phosphate 5-kinase isoform 1
NCBI Official Synonym Full Names
phosphoinositide kinase, FYVE type zinc finger containing
NCBI Official Symbol
Pikfyve  [Similar Products]
NCBI Official Synonym Symbols
p235; Pip5k; Pip5k3; Pipk5k3; PipkIII; 5230400C17Rik
  [Similar Products]
NCBI Protein Information
1-phosphatidylinositol 3-phosphate 5-kinase
UniProt Protein Name
1-phosphatidylinositol 3-phosphate 5-kinase
UniProt Synonym Protein Names
FYVE finger-containing phosphoinositide kinase; PIKfyve; Phosphatidylinositol 3-phosphate 5-kinase type III; PIPkin-III; Type III PIP kinase; p235
UniProt Gene Name
Pikfyve  [Similar Products]
UniProt Synonym Gene Names
Kiaa0981; Pip5k3; Phosphatidylinositol 3-phosphate 5-kinase; PIPkin-III; Type III PIP kinase  [Similar Products]
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UniProt Comments for PIKFYVE
The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Catalyzes the phosphorylation of phosphatidylinositol 3-phosphate on the fifth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 3,5-bisphosphate. Required for endocytic-vacuolar pathway and nuclear migration. The product of the reaction it catalyzes functions as an important regulator of vacuole homeostasis perhaps by controlling membrane flux to and/or from the vacuole.
Research Articles on PIKFYVE
1. this study shows that PIKfyve coordinates the neutrophil immune response through the activation of the Rac GTPase
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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