Product Name
FGF14, Polyclonal Antibody
Popular Item
Full Product Name
FGF14 Antibody
Product Synonym Names
bA397O8.2; FGF 14; FHF 4; FHF4; Fibroblast growth factor 14; Fibroblast growth factor homologous factor 4; mFHF-4(1B); MGC119129; MGC129318; MGC129319; RP11-397O8.6; SCA27
Product Gene Name
anti-FGF14 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q92915
Species Reactivity
Human, Mouse, Rat
Specificity
FGF14 antibody detects endogenous levels of total FGF14
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (lot specific)
Immunogen
A synthesized peptide
Subcellular Location
Nuclear
Tissue Specificity
Nervous system.
Predicted Cross Reactivity
Pig, Horse, Rabbit
Similarity
Pig (100%), Horse (100%), Rabbit (100%)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.
Other Notes
Small volumes of anti-FGF14 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-FGF14 antibody
Function: Probably involved in nervous system development and function.
Subunit Structure: Interacts with SCN8A (PubMed:26900580).
Similarity: Belongs to the heparin-binding growth factors family.
Applications Tested/Suitable for anti-FGF14 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-FGF14 antibody
WB: 1:500-1:2000
Western Blot (WB) of anti-FGF14 antibody
Western blot analysis of FGF14 expression in Mouse brain lysate (in RIPA buffer), The lane on the left is treated with the antigen-specific peptide.

NCBI/Uniprot data below describe general gene information for FGF14. It may not necessarily be applicable to this product.
NCBI Accession #
NP_004106.1
[Other Products]
NCBI GenBank Nucleotide #
NM_004115.3
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UniProt Primary Accession #
Q92915
[Other Products]
UniProt Secondary Accession #
Q86YN7; Q96QX6[Other Products]
UniProt Related Accession #
Q92915[Other Products]
Molecular Weight
Observed: 28 kDa
Predicted: 28 kDa
NCBI Official Full Name
fibroblast growth factor 14 isoform 1A
NCBI Official Synonym Full Names
fibroblast growth factor 14
NCBI Official Symbol
FGF14 [Similar Products]
NCBI Official Synonym Symbols
FHF4; FHF-4; SCA27; FGF-14
[Similar Products]
NCBI Protein Information
fibroblast growth factor 14
UniProt Protein Name
Fibroblast growth factor 14
UniProt Synonym Protein Names
Fibroblast growth factor homologous factor 4; FHF-4
Protein Family
Fibroblast growth factor
UniProt Gene Name
FGF14 [Similar Products]
UniProt Synonym Gene Names
FHF4; FGF-14; FHF-4 [Similar Products]
NCBI Summary for FGF14
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of
biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. A mutation in this gene is associated with autosomal dominant cerebral ataxia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for FGF14
Probably involved in nervous system development and function.
Research Articles on FGF14
1. The data implicate FGF14 as an organizer of channel localization in the axon initial segment and provide insight into the coordination of KCNQ and voltage-gated sodium channel conductances in the regulation of membrane potential.
Precautions
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Disclaimer
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