Full Product Name
RD3 Antibody; FITC conjugated
Product Synonym Names
Protein RD3; Retinal degeneration protein 3; RD3; C1orf36
Product Gene Name
anti-RD3 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q7Z3Z2
Species Reactivity
Human, mouse
Purity/Purification
>95%,Protein G purified
Immunogen
Recombinant human Protein RD3 protein
Storage Buffer
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-160714 / sc-160715 / sc-160716
Preparation and Storage
Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-RD3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-RD3 antibody
ELISA (EIA)
NCBI/Uniprot data below describe general gene information for RD3. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001158160.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001164688.1
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UniProt Primary Accession #
Q7Z3Z2
[Other Products]
UniProt Secondary Accession #
A8K595[Other Products]
UniProt Related Accession #
Q7Z3Z2[Other Products]
Molecular Weight
22,704 Da
NCBI Official Full Name
protein RD3
NCBI Official Synonym Full Names
retinal degeneration 3
NCBI Official Symbol
RD3 [Similar Products]
NCBI Official Synonym Symbols
LCA12; C1orf36
[Similar Products]
NCBI Protein Information
protein RD3
UniProt Protein Name
Protein RD3
UniProt Synonym Protein Names
Retinal degeneration protein 3
UniProt Gene Name
RD3 [Similar Products]
UniProt Synonym Gene Names
C1orf36 [Similar Products]
UniProt Entry Name
RD3_HUMAN
NCBI Summary for RD3
This gene encodes a retinal protein that is associated with promyelocytic leukemia-gene product (PML) bodies in the nucleus. Mutations in this gene cause Leber congenital amaurosis type 12, a disease that results in retinal degeneration. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]
UniProt Comments for RD3
RD3: Defects in RD3 are the cause of Leber congenital amaurosis type 12 (LCA12). LCA designates a clinically and genetically heterogeneous group of childhood retinal degenerations, generally inherited in an autosomal recessive manner. Affected infants have little or no retinal photoreceptor function as tested by electroretinography. LCA represents the most common genetic cause of congenital visual impairment in infants and children.
Chromosomal Location of Human Ortholog: 1q32.3
Molecular Function: protein binding
Biological Process: response to stimulus; retina development in camera-type eye; visual perception
Disease: Leber Congenital Amaurosis 12
Research Articles on RD3
1. This study reports the results of an international study aimed at delineating the clinical and molecular spectrum of RD3 mutations in retinal dystrophies.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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