Product Name
MC4 Receptor (MC4R), Polyclonal Antibody
Full Product Name
Anti-MC4 Receptor Rabbit pAb
Product Synonym Names
Melanocortin 4 receptor
Product Gene Name
anti-MC4R antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P32245
Species Reactivity
Human, Mouse, Rat
Specificity
MC4 Receptor Antibody detects endogenous levels of total MC4 Receptor
Purity/Purification
Affinity Chromatography
Form/Format
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen
A synthesized peptide derived from human MC4 Receptor
Preparation and Storage
Store at 4 degree C for short term.
Store at-20 degree C for long term.
Avoid freeze/thaw cycle.
Other Notes
Small volumes of anti-MC4R antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-MC4R antibody
Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. This receptor is mediated by G proteins that stimulate adenylate cyclase.
Applications Tested/Suitable for anti-MC4R antibody
Western Blot (WB)
Application Notes for anti-MC4R antibody
WB: 1:500-1:2000
Western Blot (WB) of anti-MC4R antibody
Western blot analysis of MC4 Receptor expression in (1) MCF7 cell lysate; (2) RAW264.7 cell lysate.
NCBI/Uniprot data below describe general gene information for MC4R. It may not necessarily be applicable to this product.
NCBI Accession #
NP_005903.2
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NCBI GenBank Nucleotide #
NM_005912.2
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UniProt Primary Accession #
P32245
[Other Products]
UniProt Secondary Accession #
Q16317; Q3MIJ6; B2RAC3[Other Products]
UniProt Related Accession #
P32245[Other Products]
NCBI Official Full Name
melanocortin receptor 4
NCBI Official Synonym Full Names
melanocortin 4 receptor
NCBI Official Symbol
MC4R [Similar Products]
NCBI Protein Information
melanocortin receptor 4
UniProt Protein Name
Melanocortin receptor 4
Protein Family
Melanocortin receptor
UniProt Gene Name
MC4R [Similar Products]
UniProt Synonym Gene Names
MC4-R [Similar Products]
NCBI Summary for MC4R
The protein encoded by this gene is a membrane-bound receptor and member of the melanocortin receptor family. The encoded protein interacts with adrenocorticotropic and MSH hormones and is mediated by G proteins. This is an intronless gene. Defects in this gene are a cause of autosomal dominant obesity. [provided by RefSeq, Jan 2010]
UniProt Comments for MC4R
Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. Plays a central role in energy homeostasis and somatic growth. This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP).
Research Articles on MC4R
1. Significant association between MC4R polymorphism and the risk of childhood obesity and BMI z-score (meta-analysis)
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
