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COL4A5, Polyclonal Antibody

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产品名称: COL4A5, Polyclonal Antibody
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简单介绍

COL4A5, Polyclonal Antibody


COL4A5, Polyclonal Antibody  的详细介绍
Product Name

COL4A5, Polyclonal Antibody

Full Product Name

COL4A5 Antibody - middle region

Product Gene Name

anti-COL4A5 antibody

[Similar Products]
Product Synonym Gene Name
ATS; ASLN; CA54[Similar Products]
Antibody/Peptide Pairs
COL4A5 peptide (MBS3246308) is used for blocking the activity of COL4A5 antibody (MBS3221574)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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Immunogen Sequence
Synthetic peptide located within the following region: PGPPGSPGDK GLQGEQGVKG DKGDTCFNCI GTGISGPPGQ PGLPGLPGPP
3D Structure
ModBase 3D Structure for Q49AM6
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Affinity purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human COL4A5
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-COL4A5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for
anti-COL4A5 antibody
This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Mutations in this gene are associated with X-linked Alport syndrome, also known as hereditary nephritis. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. Alternatively spliced transcript variants have been identified for this gene.
Product Categories/Family for anti-COL4A5 antibody
Polyclonal; Disease Related;
Applications Tested/Suitable for anti-COL4A5 antibody
Western Blot (WB)

Western Blot (WB) of anti-COL4A5 antibody
Host: Rabbit
Target Name: COL4A5
Sample Tissue: Human ACHN Whole Cell lysates
Antibody Dilution: 1ug/ml
anti-COL4A5 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for COL4A5. It may not necessarily be applicable to this product.
NCBI GI #
4502955
NCBI GeneID
1287
NCBI Accession #
NP_000486.1 [Other Products]
NCBI GenBank Nucleotide #
NM_000495.4 [Other Products]
UniProt Primary Accession #
Q49AM6 [Other Products]
UniProt Related Accession #
P29400[Other Products]
Molecular Weight
76 kDa
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NCBI Official Full Name
collagen alpha-5(IV) chain isoform 1
NCBI Official Synonym Full Names
collagen type IV alpha 5 chain
NCBI Official Symbol
COL4A5  [Similar Products]
NCBI Official Synonym Symbols
ATS; ASLN; ATS1; CA54
  [Similar Products]
NCBI Protein Information
collagen alpha-5(IV) chain
Protein Family
Collagen
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NCBI Summary for COL4A5
This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Mutations in this gene are associated with X-linked Alport syndrome, also known as hereditary nephritis. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Aug 2010]
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Research Articles on COL4A5
1. Case Reports: female X-linked Alport syndrome patients with somatic mosaic variants in COL4A5. Phenotype severity in females could be affected by modifier gene variants.
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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