Full Product Name
GORAB Antibody
Product Synonym Names
GORAB; NTKLBP1; SCYL1BP1; RAB6-interacting golgin; N-terminal kinase-like-binding protein 1; NTKL-BP1; NTKL-binding protein 1; hNTKL-BP1; SCY1-like 1-binding protein 1; SCYL1-BP1; SCYL1-binding protein 1
Product Gene Name
anti-GORAB antibody
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q5T7V8
Species Reactivity
Human, Mouse, Rat
Specificity
GORAB Antibody detects endogenous levels of GORAB protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using peptide.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1 mg/ml (lot specific)
Target Modification
Unmodified/Total
Immunogen
The antiserum was produced against synthesized peptide derived from the N-terminal region of human GORAB.
Preparation and Storage
Stable at -20 degree C for at least 1 year.
Other Notes
Small volumes of anti-GORAB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-GORAB antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-GORAB antibody
WB: 1:500~1:1000
ELISA: 1:10000
Western Blot (WB) of anti-GORAB antibody
Western blot analysis of lysate from AD293 cells, using GORAB Antibody.
NCBI/Uniprot data below describe general gene information for GORAB. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001139511.1
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NCBI GenBank Nucleotide #
NM_001146039.1
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UniProt Primary Accession #
Q5T7V8
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UniProt Secondary Accession #
Q49A22; Q6P1P9; Q9HAE6; Q9Y350[Other Products]
UniProt Related Accession #
Q5T7V8[Other Products]
NCBI Official Full Name
RAB6-interacting golgin isoform b
NCBI Official Synonym Full Names
golgin, RAB6 interacting
NCBI Official Symbol
GORAB [Similar Products]
NCBI Official Synonym Symbols
GO; NTKLBP1; SCYL1BP1
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NCBI Protein Information
RAB6-interacting golgin
UniProt Protein Name
RAB6-interacting golgin
UniProt Synonym Protein Names
N-terminal kinase-like-binding protein 1; NTKL-BP1; NTKL-binding protein 1; hNTKL-BP1; SCY1-like 1-binding protein 1; SCYL1-BP1; SCYL1-binding protein 1
Protein Family
RAB6-interacting golgin
UniProt Gene Name
GORAB [Similar Products]
UniProt Synonym Gene Names
NTKLBP1; SCYL1BP1; NTKL-BP1; NTKL-binding protein 1; hNTKL-BP1; SCYL1-BP1; SCYL1-binding protein 1 [Similar Products]
NCBI Summary for GORAB
This gene encodes a member of the golgin family, a group of coiled-coil proteins localized to the Golgi. The encoded protein may function in the secretory pathway. The encoded protein, which also localizes to the cytoplasm, was identified by interactions with the N-terminal kinase-like protein, and thus it may function in mitosis. Mutations in this gene have been associated with geroderma osteodysplastica. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2009]
Research Articles on GORAB
1. in the present study a de novo deletion on 1q23.3-q24.2 combined with a GORAB missense mutation leads to a distinctive phenotype with features from Gerodermia osteodysplastica and also short stature, cutis laxa, frequent fractures, facial dysmorphism, cup-shaped ears and intellectual disability
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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