Product Name
Zinc finger protein 57 homolog (ZFP57), Recombinant Protein
Full Product Name
Recombinant Human Zinc finger protein 57 homolog (ZFP57)
Product Gene Name
ZFP57 recombinant protein
[Similar Products]
Product Synonym Gene Name
ZFP57[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-452aa, full length protein
Sequence
MAAGEPRSLL FFQKPVTFED VAVNFTQEEW DCLDASQRVL YQDVMSETFK NLTSVARIFL HKPELITKLE QEEEQWRETR VLQASQAGPP FFCYTCGKCF SRRSYLYSHQ FVHNPKLTNS CSQCGKLFRS PKSLSYHRRM HLGERPFCCT LCDKTYCDAS GLSRHRRVHL GYRPHSCSVC GKSFRDQSEL KRHQKIHQNQ EPVDGNQECT LRIPGTQAEF QTPIARSQRS IQGLLDVNHA PVARSQEPIF RTEGPMAQNQ ASVLKNQAPV TRTQAPITGT LCQDARSNSH PVKPSRLNVF CCPHCSLTFS KKSYLSRHQK AHLTEPPNYC FHCSKSFSSF SRLVRHQQTH WKQKSYLCPI CDLSFGEKEG LMDHWRGYKG KDLCQSSHHK CRVILGQWLG FSHDVPTMAG EEWKHGGDQS PPRIHTPRRR GLREKACKGD KTKEAVSILK HK
3D Structure
ModBase 3D Structure for Q9NU63
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of ZFP57 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for ZFP57. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001103279.2
[Other Products]
NCBI GenBank Nucleotide #
NM_001109809.2
[Other Products]
UniProt Primary Accession #
Q9NU63
[Other Products]
UniProt Secondary Accession #
Q5SSB1; B0S894; B0V254; B2RXJ7[Other Products]
UniProt Related Accession #
Q9NU63[Other Products]
Molecular Weight
61,358 Da
NCBI Official Full Name
zinc finger protein 57 homolog
NCBI Official Synonym Full Names
ZFP57 zinc finger protein
NCBI Official Symbol
ZFP57 [Similar Products]
NCBI Official Synonym Symbols
TNDM1; ZNF698; C6orf40; bA145L22; bA145L22.2
[Similar Products]
NCBI Protein Information
zinc finger protein 57 homolog
UniProt Protein Name
Zinc finger protein 57 homolog
UniProt Synonym Protein Names
Zinc finger protein 698
Protein Family
Zinc finger protein
UniProt Gene Name
ZFP57 [Similar Products]
UniProt Synonym Gene Names
C6orf40; ZNF698; Zfp-57 [Similar Products]
NCBI Summary for ZFP57
The protein encoded by this gene is a zinc finger protein containing a KRAB domain. Studies in mouse suggest that this protein may function as a transcriptional repressor. Mutations in this gene have been associated with transient neonatal diabetes mellitus type 1 (TNDM1).[provided by RefSeq, Sep 2009]
UniProt Comments for ZFP57
Binds to a 5'-TGCCGC-3' consensus sequence and recognizes the methylated CpG within this element (). Transcription regulator required to maintain maternal and paternal gene imprinting, a process by which gene expression is restricted in a parent of origin-specific manner by epigenetic modification of genomic DNA and chromatin, including DNA methylation. Acts by controlling DNA methylation during the earliest multicellular stages of development at multiple imprinting control regions. Required for the establishment of maternal methylation imprints at SNRPN locus. Acts as a transcriptional repressor in Schwann cells.
Research Articles on ZFP57
1. transient neonatal diabetes type 1 is associated with ZFP57 mutations
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
