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Orexin A, Polyclonal Antibody

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产品名称: Orexin A, Polyclonal Antibody
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简单介绍

Orexin A, Polyclonal Antibody


Orexin A, Polyclonal Antibody  的详细介绍
Product Name

Orexin A (OXA), Polyclonal Antibody

Full Product Name

Polyclonal Antibody to Orexin A (OXA)

Product Gene Name

anti-OXA antibody

[Similar Products]
Matching Pairs
Unconjugated Antibody: Orexin A (MBS2026540)
Immunogen: Orexin A (MBS2029882)
Matching Pairs
Unconjugated Antibody: Orexin A (MBS2026540)
APC-CY7 Conjugated Antibody: Orexin A (OXA) (MBS2044931)
Matching Pairs
Unconjugated Antibody: Orexin A (MBS2026540)
PE Conjugated Antibody: Orexin A (OXA) (MBS2044932)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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Immunogen Sequence
Antigen: The target protein is fused with two N-terminal Tags, His-tag and GST-tag and its sequence is listed below.
MSPILGYWKI KGLVQPTRLL LEYLEEKYEE HLYERDEGDK WRNKKFELGL EFPNLPYYID GDVKLTQSMA IIRYIADKHN MLGGCPKERA EISMLEGAVL DIRYGVSRIA YSKDFETLKV DFLSKLPEML KMFEDRLCHK TYLNGDHVTH PDFMLYDALD VVLYMDPMCL DAFPKLVCFK KRIEAIPQID KYLKSSKYIA WPLQGWQATF GGGDHPPKSD GSTSGSGHHH HHHSAGLVPR GSTAIGMKET AAAKFERQHM DSPDLGTGGG SGIEGRGSMG YRGSEF-AQP LPDCCR QKTCSCRLYE LLHGAGNHAA GILTLGKRRP GPPGLQGRLQ RLLQANGNHA AGILTMGRRA
3D Structure
ModBase 3D Structure for O55232
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Rat
Specificity
The antibody is a rabbit polyclonal antibody raised against OXA. It has beenselected for its ability to recognize OXA in immunohistochemical staining andwestern blotting.
Purity/Purification
Affinity Chromatography
Form/Format
Liquid
Concentration
200ug/ml (lot specific)
Fragment
OXA (Ala32~Ala123)
Organism Species
Rattus norvegicus (Rat)
Conjugate
No Conjugate
Immunogen
Recombinant OXA (Ala32~Ala123) expressed in E Coli.
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2044933
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Other Notes
Small volumes of anti-OXA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Applications Tested/Suitable for anti-OXA antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA)
Application Notes for anti-OXA antibody
Western blotting: 0.5-2ug/mL
Immunohistochemistry: 5-20ug/mL
Immunocytochemistry: 5-20ug/mL
Optimal working dilutions must be determined by end user.

Western Blot (WB) of anti-OXA antibody
Western Blot: Sample: Recombinant protein.
anti-OXA antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-OXA antibody
DAB staining on fromalin fixed paraffin- embedded liver tissue)
anti-OXA antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-OXA antibody
DAB staining on IHC-P; Samples: Rat Brain Tissue)
anti-OXA antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for OXA. It may not necessarily be applicable to this product.
NCBI GI #
6981016
NCBI GeneID
25723
NCBI Accession #
NP_037311.1 [Other Products]
NCBI GenBank Nucleotide #
NM_013179.2 [Other Products]
UniProt Primary Accession #
O55232 [Other Products]
UniProt Related Accession #
O55232[Other Products]
Molecular Weight
13,645 Da
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NCBI Official Full Name
orexin
NCBI Official Synonym Full Names
hypocretin neuropeptide precursor
NCBI Official Symbol
Hcrt  [Similar Products]
NCBI Official Synonym Symbols
orexin-A
  [Similar Products]
NCBI Protein Information
orexin
UniProt Protein Name
Orexin
UniProt Synonym Protein Names
Hypocretin; Hcrt
UniProt Gene Name
Hcrt  [Similar Products]
UniProt Synonym Gene Names
Ox; Ppox; Hcrt; Hcrt1; Hcrt2  [Similar Products]
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NCBI Summary for OXA
neuropeptide; involved in feeding behavior and hormone secretion regulation [RGD, Feb 2006]
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UniProt Comments for OXA
Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. A modulation effect on luteinizing hormone-releasing hormone (LHRH) secretion also suggests a more minor contribution to the regulation of reproductive function. Orexin-A binds to both OX1R and OX2R with a high affinity, whereas orexin-B binds only to OX2R with a similar high affinity.
Research Articles on OXA
1. A functional link between AMPK and orexin mediates the effect of BMP8B on energy balance.
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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