Full Product Name
NOM1 Antibody - middle region
Product Gene Name
anti-NOM1 antibody
[Similar Products]
Product Synonym Gene Name
SGD1; C7orf3; PPP1R113[Similar Products]
Antibody/Peptide Pairs
NOM1 peptide (MBS3248079) is used for blocking the activity of NOM1 antibody (MBS3223444)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Synthetic peptide located within the following region: GLGGRSGAEE ASGHRQDTEE RARPAPSRDP SPPRKPRPSR VKAKATAATA
3D Structure
ModBase 3D Structure for Q5C9Z4
Purity/Purification
Affinity purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human NOM1
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-NOM1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-NOM1 antibody
Proteins that contain MIF4G and/or MA3 domains, such as NOM1, function in protein translation. These domains include s for members of the EIF4A family of ATP-dependent DEAD box RNA helicases .
Product Categories/Family for anti-NOM1 antibody
Polyclonal; RNA Binding Proteins; Transcription Regulation;
Applications Tested/Suitable for anti-NOM1 antibody
Western Blot (WB)
Western Blot (WB) of anti-NOM1 antibody
Host: Rabbit
Target Name: NOM1
Sample Tissue: Human 293T Whole Cell lysates
Antibody Dilution: 1ug/ml
NCBI/Uniprot data below describe general gene information for NOM1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_612409.1
[Other Products]
NCBI GenBank Nucleotide #
NM_138400.1
[Other Products]
UniProt Primary Accession #
Q5C9Z4
[Other Products]
UniProt Related Accession #
Q5C9Z4[Other Products]
NCBI Official Full Name
nucleolar MIF4G domain-containing protein 1 isoform 1
NCBI Official Synonym Full Names
nucleolar protein with MIF4G domain 1
NCBI Official Symbol
NOM1 [Similar Products]
NCBI Official Synonym Symbols
SGD1; C7orf3; PPP1R113
[Similar Products]
NCBI Protein Information
nucleolar MIF4G domain-containing protein 1
UniProt Protein Name
Nucleolar MIF4G domain-containing protein 1
UniProt Synonym Protein Names
SGD1 homolog
Protein Family
Nucleolar MIF4G domain-containing protein
UniProt Gene Name
NOM1 [Similar Products]
UniProt Synonym Gene Names
C7orf3 [Similar Products]
UniProt Entry Name
NOM1_HUMAN
NCBI Summary for NOM1
Proteins that contain MIF4G (middle of eIF4G (MIM 600495)) and/or MA3 domains, such as NOM1, function in protein translation. These domains include s for members of the EIF4A family of ATP-dependent DEAD box RNA helicases (see EIF4A1; MIM 602641) (Simmons et al., 2005 [PubMed 15715967]).[supplied by OMIM, Mar 2008]
UniProt Comments for NOM1
NOM1: a nucleolar protein that binds eIF4A and encoded within the chromosome 7q36 breakpoint region associated with pediatric acute myeloid leukemia. Contains an MIF4G and an MA3 domain. MIF4G and MA3 domains bind proteins of the eIF4A family of ATP-dependent DEAD-box RNA helicases required for both translation and nonsense-mediated decay. MIF4G domains are found in several proteins involved in RNA metabolism, including eIF4G, eIF-2b, UPF2, and nuclear cap-binding proteins.
Protein type: Unknown function; Nucleolus
Chromosomal Location of Human Ortholog: 7q36.3
Cellular Component: nucleolus; nucleus
Molecular Function: protein binding
Research Articles on NOM1
1. demonstrate direct physical interactions between yeast Sgd1p and Fal1p, and between their human orthologs (NOM1 and eIF4AIII) in vitro and in vivo, identifying human NOM1 as a missing eIF4G-like interacting partner of eIF4AIII
Precautions
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Disclaimer
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