Product Name
NOM1, Blocking Peptide
Full Product Name
NOM1 Peptide - middle region
Product Gene Name
NOM1 blocking peptide
[Similar Products]
Product Synonym Gene Name
SGD1; C7orf3; PPP1R113[Similar Products]
NOM1 peptide (MBS3248079) is used for blocking the activity of NOM1 antibody (MBS3223444)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
Synthetic peptide located within the following region: GLGGRSGAEE ASGHRQDTEE RARPAPSRDP SPPRKPRPSR VKAKATAATA
3D Structure
ModBase 3D Structure for Q5C9Z4
Form/Format
Lyophilized powder
Preparation and Storage
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.
Other Notes
Small volumes of NOM1 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
NOM1 blocking peptide
This is a synthetic peptide designed for use in combination with anti- NOM1 Antibody, made
Target Description: Proteins that contain MIF4G and/or MA3 domains, such as NOM1, function in protein translation. These domains include s for members of the EIF4A family of ATP-dependent DEAD box RNA helicases .
Product Categories/Family for NOM1 blocking peptide
Peptide
NCBI/Uniprot data below describe general gene information for NOM1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_612409.1
[Other Products]
NCBI GenBank Nucleotide #
NM_138400.1
[Other Products]
UniProt Primary Accession #
Q5C9Z4
[Other Products]
UniProt Related Accession #
Q5C9Z4[Other Products]
NCBI Official Full Name
nucleolar MIF4G domain-containing protein 1 isoform 1
NCBI Official Synonym Full Names
nucleolar protein with MIF4G domain 1
NCBI Official Symbol
NOM1 [Similar Products]
NCBI Official Synonym Symbols
SGD1; C7orf3; PPP1R113
[Similar Products]
NCBI Protein Information
nucleolar MIF4G domain-containing protein 1
UniProt Protein Name
Nucleolar MIF4G domain-containing protein 1
UniProt Synonym Protein Names
SGD1 homolog
Protein Family
Nucleolar MIF4G domain-containing protein
UniProt Gene Name
NOM1 [Similar Products]
UniProt Synonym Gene Names
C7orf3 [Similar Products]
UniProt Entry Name
NOM1_HUMAN
NCBI Summary for NOM1
Proteins that contain MIF4G (middle of eIF4G (MIM 600495)) and/or MA3 domains, such as NOM1, function in protein translation. These domains include s for members of the EIF4A family of ATP-dependent DEAD box RNA helicases (see EIF4A1; MIM 602641) (Simmons et al., 2005 [PubMed 15715967]).[supplied by OMIM, Mar 2008]
UniProt Comments for NOM1
NOM1: a nucleolar protein that binds eIF4A and encoded within the chromosome 7q36 breakpoint region associated with pediatric acute myeloid leukemia. Contains an MIF4G and an MA3 domain. MIF4G and MA3 domains bind proteins of the eIF4A family of ATP-dependent DEAD-box RNA helicases required for both translation and nonsense-mediated decay. MIF4G domains are found in several proteins involved in RNA metabolism, including eIF4G, eIF-2b, UPF2, and nuclear cap-binding proteins.
Protein type: Unknown function; Nucleolus
Chromosomal Location of Human Ortholog: 7q36.3
Cellular Component: nucleolus; nucleus
Molecular Function: protein binding
Research Articles on NOM1
1. demonstrate direct physical interactions between yeast Sgd1p and Fal1p, and between their human orthologs (NOM1 and eIF4AIII) in vitro and in vivo, identifying human NOM1 as a missing eIF4G-like interacting partner of eIF4AIII
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
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