Cyclin-related protein FAM58A (FAM58A), ELISA Kit

For Research Use Only. Not for use in diagnostic procedures.

Store all reagents at 2-8 degree C.

We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.

Small volumes of FAM58A elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS7201195 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Cyclin-related protein FAM58A (FAM58A) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing FAM58A. The ELISA analytical biochemical technique of the MBS7201195 kit is based on FAM58A antibody-FAM58A antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect FAM58A antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, FAM58A. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

26,114 Da[Similar Products]

family with sequence similarity 58, member A

cyclin-related protein FAM58A; cyclin M; CDK10-activating cyclin

Cyclin-related protein FAM58A

FA58A_HUMAN

Mutations in this gene have been shown to cause an X-linked dominant STAR syndrome that typically manifests syndactyly, telecanthus and anogenital and renal malformations. The protein encoded by this gene contains a cyclin-box-fold domain which suggests it may have a role in controlling nuclear cell division cycles. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]

FAM58B: May have a role in cell proliferation. Defects in FAM58A are the cause of toe syndactyly, telecanthus, and anogenital and renal malformations (STAR); also known as STAR syndrome or syndactyly with renal and anogenital malformations. Belongs to the cyclin family. Cyclin-like FAM58 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell cycle regulation

Chromosomal Location of Human Ortholog: Xq28

Cellular Component: DNA-directed RNA polymerase II, holoenzyme

Molecular Function: protein binding; protein kinase binding; protein kinase activator activity

Biological Process: regulation of transcription, DNA-dependent; positive regulation of MAPKKK cascade; positive regulation of protein kinase activity; regulation of cyclin-dependent protein kinase activity

Disease: Toe Syndactyly, Telecanthus, And Anogenital And Renal Malformations

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