14-3-3 protein zeta/delta, ELISA Kit

For Research Use Only. Not for use in diagnostic procedures.

Store all reagents at 2-8 degree C.

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Small volumes of YWHAZ elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS2606917 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the 14-3-3 protein zeta/delta (YWHAZ) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing YWHAZ. The ELISA analytical biochemical technique of the MBS2606917 kit is based on YWHAZ antibody-YWHAZ antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect YWHAZ antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, YWHAZ. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

19,333 Da

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta

14-3-3 protein zeta/delta

14-3-3 protein zeta/delta

KCIP-1  [Similar Products]

1433Z_HUMAN

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene. [provided by RefSeq, Oct 2008]

14-3-3 zeta: a protein of the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. A multifunctional regulator of the cell signaling processes. Phosphorylation apparently disrupts homodimerization.

Protein type: Adaptor/scaffold; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 8q23.1

Cellular Component: cytoplasm; cytoplasmic vesicle membrane; cytosol; extracellular space; focal adhesion; melanosome; mitochondrion; nucleoplasm; nucleus

Molecular Function: identical protein binding; protein binding; protein domain specific binding; protein kinase binding; transcription factor binding; ubiquitin protein ligase binding

Biological Process: apoptosis; blood coagulation; establishment of Golgi localization; gene expression; negative regulation of apoptosis; platelet activation; programmed cell death; protein targeting; regulation of mRNA stability; signal transduction; small GTPase mediated signal transduction; transcription initiation from RNA polymerase II promoter

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