Full Product Name
Human INSL3 Polyclonal Antibody
Product Synonym Names
RLF; RLNL; Leydig insulin-like peptide; Relaxin-like factor; Ley-I-L
Product Gene Name
anti-INSL3 antibody
[Similar Products]
Matching Pairs
Antibody: INSL3 (MBS2892051)
Antigen: Insulin-like 3 (MBS2888599)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P51460
Purity/Purification
Immunogen Affinity Purified
Form/Format
Liquid; 0.1MxPBS, 50% Glycerol, pH7.5
Concentration
200 ug/ml (lot specific)
Immunogen
Recombinant Human INSL3 Protein
Preparation and Storage
Store at 4 degree C for frequent use. Store at -20 degree C to -70 degree C for 6 months.
Other Notes
Small volumes of anti-INSL3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-INSL3 antibody
Western Blot (WB), Immunohistochemistry (IHC)
NCBI/Uniprot data below describe general gene information for INSL3. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001252516.1
[Other Products]
NCBI GenBank Nucleotide #
NP_001252516.1
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UniProt Primary Accession #
P51460
[Other Products]
UniProt Related Accession #
P51460[Other Products]
NCBI Official Full Name
insulin-like 3 isoform 1
NCBI Official Synonym Full Names
insulin like 3
NCBI Official Symbol
INSL3 [Similar Products]
NCBI Official Synonym Symbols
RLF; RLNL; ley-I-L
[Similar Products]
NCBI Protein Information
insulin-like 3
UniProt Protein Name
Insulin-like 3
UniProt Synonym Protein Names
Leydig insulin-like peptide; Ley-I-L
UniProt Gene Name
INSL3 [Similar Products]
UniProt Synonym Gene Names
RLF; RLNL; Ley-I-L [Similar Products]
NCBI Summary for INSL3
This gene encodes a member of the insulin-like hormone superfamily. The encoded protein is mainly produced in gonadal tissues. Studies of the mouse counterpart suggest that this gene may be involved in the development of urogenital tract and female fertility. This protein may also act as a hormone to regulate growth and differentiation of gubernaculum, and thus mediating intra-abdominal testicular descent. Mutations in this gene may lead to cryptorchidism. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2012]
UniProt Comments for INSL3
Seems to play a role in testicular function. May be a trophic hormone with a role in testicular descent in fetal life. Is a ligand for LGR8 receptor.
Research Articles on INSL3
1. Variants of the INSL3 gene are prevalent in patients with testicular torsion instead of healthy subjects.
Precautions
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Disclaimer
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