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ABHD6, Polyclonal Antibody

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产品名称: ABHD6, Polyclonal Antibody
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简单介绍

ABHD6, Polyclonal Antibody


ABHD6, Polyclonal Antibody  的详细介绍
Product Name

ABHD6, Polyclonal Antibody

Full Product Name

Goat anti-ABHD6 Antibody

Product Synonym Names
ABHD6; abhydrolase domain containing 6; lipase protein; ABHD6 antibody; abhydrolase domain containing 6 antibody; lipase protein antibody
Product Gene Name

anti-ABHD6 antibody

[Similar Products]
Antibody/Peptide Pairs
ABHD6 peptide (MBS425493) is used for blocking the activity of ABHD6 antibody (MBS422076)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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Immunogen Sequence
SEKSRYSLHQ NMDK
Clonality
Polyclonal
Host
Goat
Species Reactivity
Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration
100ug specific antibody in 200ul (lot specific)
Immunogen
Peptide with sequence C-SEKSRYSLHQNMDK, from the internal region of the protein sequence according to NP_065727.3.
Epitope
Internal region
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-ABHD6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Applications Tested/Suitable for anti-ABHD6 antibody
Peptide ELISA (EIA)
Application Notes for anti-ABHD6 antibody
Peptide ELISA: Antibody detection limit dilution 1: 32000.
Western Blot: Preliminary experiments in Human Brain (Cerebellum, Amygdala, Substantia Nigra) lysates gave no specific signal but low background (at antibody concentration up to 1ug/ml).
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NCBI/Uniprot data below describe general gene information for ABHD6. It may not necessarily be applicable to this product.
NCBI GI #
47271495
NCBI GeneID
57406
NCBI Accession #
NP_065727.3 [Other Products]
NCBI GenBank Nucleotide #
NM_020676.4 [Other Products]
UniProt Secondary Accession #
Q6ZMF7; B2R7Y9[Other Products]
UniProt Related Accession #
Q9BV23[Other Products]
Molecular Weight
38,331 Da
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NCBI Official Full Name
abhydrolase domain containing 6
NCBI Official Synonym Full Names
abhydrolase domain containing 6
NCBI Official Symbol
ABHD6  [Similar Products]
NCBI Protein Information
monoacylglycerol lipase ABHD6
UniProt Protein Name
Monoacylglycerol lipase ABHD6
UniProt Synonym Protein Names
2-arachidonoylglycerol hydrolase
Protein Family
Monoacylglycerol lipase
UniProt Gene Name
ABHD6  [Similar Products]
UniProt Entry Name
ABHD6_HUMAN
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UniProt Comments for ABHD6
ABHD6: Has 2-arachidonoylglycerol hydrolase activity. May be a regulator of endocannabinoid signaling pathways. Belongs to the AB hydrolase superfamily.

Protein type: Lipase; EC 3.1.1.23; Membrane protein, integral

Chromosomal Location of Human Ortholog: 3p14.3

Cellular Component: integral to membrane; mitochondrion; plasma membrane

Molecular Function: acylglycerol lipase activity; phospholipase activity

Biological Process: acylglycerol catabolic process; negative regulation of cell migration; phospholipid catabolic process; positive regulation of lipid biosynthetic process
Research Articles on ABHD6
1. data suggest that ABHD6 controls BMP catabolism and is therefore part of the late endosomal/lysosomal lipid-sorting machinery
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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