Product Name
IL-31, ELISA Kit
Full Product Name
IL-31 (Human) OmniKine ELISA Kit
Product Synonym Names
Interleukin-31
Product Gene Name
IL-31 elisa kit
[Similar Products]
Product Synonym Gene Name
IL31[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sample Manual Insert
Download Sample PDF Manual View Sample PDF Manual
Request for Current Manual Insert
Request Current Manual
3D Structure
ModBase 3D Structure for Q6EBC2
Specificity
The OmniKine Human IL-31 ELISA is capable of recognizing both recombinant and naturally produced Human IL-31 proteins. The antigens listed below were tested at 50 ng/ml and did not exhibit significant cross reactivity or interference.
Human: CNTF, CT-1, G-CSF, GM-CSF, IL-3, IL-6, IL-6Ralpha, IL-11, IL-12, M-CSF, OSM
Murine: CT-1, IL-6, IL-31
Rat: IL-6
Form/Format
12 x 8-Well Microstrips
Samples
Plasma, serum, lysate
Assay Type
Sandwich ELISA
Detection Range
32-4000 pg/ml
Sensitivity
32-4000 pg/ml
Detection Method
Colorimetric 450 nm
Preparation and Storage
Store at 4 degree C for 6 months.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of IL-31 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for IL-31 purchase
MBS9501863 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the IL-31, ELISA Kit target analytes in
biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing IL-31. The ELISA analytical biochemical technique of the MBS9501863 kit is based on IL-31 antibody-IL-31 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect IL-31 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, IL-31. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Testing Data of IL-31 elisa kit
The OmniKine Human IL-31 ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Human IL-31 proteins within the range of 32-4000 pg/ml.
NCBI/Uniprot data below describe general gene information for IL-31. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001014358.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001014336.1
[Other Products]
UniProt Primary Accession #
Q6EBC2
[Other Products]
UniProt Secondary Accession #
A2RUQ1[Other Products]
UniProt Related Accession #
Q6EBC2[Other Products]
Molecular Weight
18,205 Da
NCBI Official Full Name
interleukin-31
NCBI Official Synonym Full Names
interleukin 31
NCBI Official Symbol
IL31 [Similar Products]
NCBI Official Synonym Symbols
IL-31
[Similar Products]
NCBI Protein Information
interleukin-31
UniProt Protein Name
Interleukin-31
UniProt Gene Name
IL31 [Similar Products]
UniProt Synonym Gene Names
IL-31 [Similar Products]
NCBI Summary for IL-31
IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma (Dillon et al., 2004 [PubMed 15184896]).[supplied by OMIM, Mar 2008]
UniProt Comments for IL-31
IL31: Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. IL31 may function in skin immunity.
Protein type: Cytokine; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 12q24.31
Cellular Component: extracellular region; extracellular space
Molecular Function: cytokine activity
Biological Process: immune system process
Research Articles on IL-31
1. This study indicated that CXCL13 rather than IL-31 may have clinical values of diagnosis and prognosis in hepatocellular carcinoma.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
