Product Name
Neuropathy Target Esterase (NTE), Antibody Pair Kit
Full Product Name
Neuropathy Target Esterase (NTE) Antibody Pair Kit (with Standard)
Product Synonym Names
PNPLA6; Sws; Patatin-Like Phospholipase Domain Containing 6
Product Gene Name
NTE antibody pair kit
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Matching Pairs
Antibody: Neuropathy Target Esterase (NTE) (MBS2103847)
Pairing: Neuropathy Target Esterase (NTE) (MBS2103847)
Comments: Matched antibody pair kit containing antibody/standard combination
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
Request Current Manual
3D Structure
ModBase 3D Structure for Q8IY17
Samples
Tissue Homogenates, Cell Lysates and Other Biological Fluids
Detection Range
0.312-20ng/mL
Standard
Recombinant NTE (Lyophilized, 1 vial-10ug)
Capture Antibody
Rabbit polyclonal antibody (Liquid, 1 vial-400mug/800muL)
Detection Antibody
Biotinylated Rabbit polyclonal antibody (Liquid, 1 vial-100mug/500muL)
Producte Usage
Raw materials can be used for preparation of 5x96T or 10x96T ELISA Kits.
Antibody Support Pack
Antibody Support Pack (Buffer Pack) is sold separately as catalog #MBS2090685
ISO Certification
Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customerâs specifications, please inquire.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of NTE antibody pair kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for NTE antibody pair kit
Enzyme & Kinase
Applications Tested/Suitable for NTE antibody pair kit
ELISA (EIA), Chemiluminescence Immunoassays (CLIA), ELISPOT, Luminex
NCBI/Uniprot data below describe general gene information for NTE. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001159586.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001166114.1
[Other Products]
UniProt Primary Accession #
Q8IY17
[Other Products]
UniProt Secondary Accession #
O60859; Q86W58; Q9UG58; A6NGQ0; B4DFB9; B7Z7T2; F5H5K9; J3KQS3[Other Products]
UniProt Related Accession #
Q8IY17[Other Products]
Molecular Weight
143,351 Da
NCBI Official Full Name
neuropathy target esterase isoform d
NCBI Official Synonym Full Names
patatin like phospholipase domain containing 6
NCBI Official Symbol
PNPLA6 [Similar Products]
NCBI Official Synonym Symbols
NTE; sws; BNHS; LNMS; OMCS; SPG39; NTEMND; iPLA2delta
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NCBI Protein Information
neuropathy target esterase
UniProt Protein Name
Neuropathy target esterase
UniProt Synonym Protein Names
Patatin-like phospholipase domain-containing protein 6
UniProt Gene Name
PNPLA6 [Similar Products]
UniProt Synonym Gene Names
NTE [Similar Products]
NCBI Summary for NTE
This gene encodes a phospholipase that deacetylates intracellular phosphatidylcholine to produce glycerophosphocholine. It is thought to function in neurite outgrowth and process elongation during neuronal differentiation. The protein is anchored to the cytoplasmic face of the endoplasmic reticulum in both neurons and non-neuronal cells. Mutations in this gene result in autosomal recessive spastic paraplegia, and the protein is the target for neurodegeneration induced by organophosphorus compounds and chemical warfare agents. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
UniProt Comments for NTE
Phospholipase B that deacylates intracellular phosphatidylcholine (PtdCho), generating glycerophosphocholine (GroPtdCho). This deacylation occurs at both sn-2 and sn-1 positions of PtdCho. Its specific chemical modification by certain organophosphorus (OP) compounds leads to distal axonopathy.
Research Articles on NTE
1. Silencing of PNPLA6, the neuropathy target esterase (NTE) codifying gene, alters early neurodevelopment.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.