Product Name
ASMT, Blocking Peptide
Full Product Name
ASMT Peptide - N-terminal region
Product Gene Name
ASMT blocking peptide
[Similar Products]
ASMT peptide (MBS3244139) is used for blocking the activity of ASMT antibody (MBS3219247)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
Synthetic peptide located within the following region: VRASAHGTEL LLDICVSLKL LKVETRGGKA FYRNTELSSD YLTTVSPTSQ
3D Structure
ModBase 3D Structure for P46597
Form/Format
Lyophilized powder
Preparation and Storage
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.
Other Notes
Small volumes of ASMT blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
ASMT blocking peptide
This is a synthetic peptide designed for use in combination with anti-ASMT Antibody, made
Target Description: This gene belongs to the methyltransferase superfamily, and is located in the pseudoautosomal region (PAR) at the end of the short arms of the X and Y chromosomes. The encoded enzyme catalyzes the final reaction in the synthesis of melatonin, and is abundant in the pineal gland. Alternatively spliced transcript variants have been noted for this gene.
Product Categories/Family for ASMT blocking peptide
Peptide
Applications Tested/Suitable for ASMT blocking peptide
Western Blot (WB)
NCBI/Uniprot data below describe general gene information for ASMT. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001164509.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001171038.2
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UniProt Primary Accession #
P46597
[Other Products]
UniProt Related Accession #
P46597[Other Products]
NCBI Official Full Name
acetylserotonin O-methyltransferase isoform 1
NCBI Official Synonym Full Names
acetylserotonin O-methyltransferase
NCBI Official Symbol
ASMT [Similar Products]
NCBI Official Synonym Symbols
ASMTY; HIOMT; HIOMTY
[Similar Products]
NCBI Protein Information
acetylserotonin O-methyltransferase
UniProt Protein Name
Acetylserotonin O-methyltransferase
UniProt Synonym Protein Names
Hydroxyindole O-methyltransferase; HIOMT
Protein Family
Acetylserotonin O-methyltransferase
UniProt Gene Name
ASMT [Similar Products]
UniProt Synonym Gene Names
HIOMT [Similar Products]
UniProt Entry Name
ASMT_HUMAN
NCBI Summary for ASMT
This gene belongs to the methyltransferase superfamily, and is located in the pseudoautosomal region (PAR) at the end of the short arms of the X and Y chromosomes. The encoded enzyme catalyzes the final reaction in the synthesis of melatonin, and is abundant in the pineal gland. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Jan 2010]
UniProt Comments for ASMT
ASMT: Produces melatonin (N-acetyl-5-methoxytryptamine) from N-acetylserotonin. Belongs to the methyltransferase superfamily. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Methyltransferase; EC 2.1.1.4; Amino Acid Metabolism - tryptophan
Chromosomal Location of Human Ortholog: Xp22.3 or Yp11.3
Cellular Component: cytosol
Molecular Function: identical protein binding; protein homodimerization activity; O-methyltransferase activity; acetylserotonin O-methyltransferase activity
Biological Process: methylation; melatonin biosynthetic process; translation; indolalkylamine biosynthetic process
Research Articles on ASMT
1. Low HIOMT expression is associated with lung cancer.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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