ASMT, Polyclonal Antibody

For Research Use Only. Not for use in diagnostic procedures.

Polyclonal

Rabbit

Affinity Purified

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Small volumes of anti-ASMT antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

This is a rabbit polyclonal antibody against ASMT. It was validated on Western Blot

Target Description: This gene belongs to the methyltransferase superfamily, and is located in the pseudoautosomal region (PAR) at the end of the short arms of the X and Y chromosomes. The encoded enzyme catalyzes the final reaction in the synthesis of melatonin, and is abundant in the pineal gland. Alternatively spliced transcript variants have been noted for this gene.

Polyclonal; RNA Binding Proteins;

Western Blot (WB)

Host: Rabbit
Target Name: ASMT
Sample Tissue: Human Fetal Kidney
Antibody Dilution: 1ug/ml

32kDa

acetylserotonin O-methyltransferase

acetylserotonin O-methyltransferase

Acetylserotonin O-methyltransferase

HIOMT  [Similar Products]

ASMT_HUMAN

This gene belongs to the methyltransferase superfamily, and is located in the pseudoautosomal region (PAR) at the end of the short arms of the X and Y chromosomes. The encoded enzyme catalyzes the final reaction in the synthesis of melatonin, and is abundant in the pineal gland. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Jan 2010]

ASMT: Produces melatonin (N-acetyl-5-methoxytryptamine) from N-acetylserotonin. Belongs to the methyltransferase superfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Methyltransferase; EC 2.1.1.4; Amino Acid Metabolism - tryptophan

Chromosomal Location of Human Ortholog: Xp22.3 or Yp11.3

Cellular Component: cytosol

Molecular Function: identical protein binding; protein homodimerization activity; O-methyltransferase activity; acetylserotonin O-methyltransferase activity

Biological Process: methylation; melatonin biosynthetic process; translation; indolalkylamine biosynthetic process

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