Full Product Name
Phospho-DOR-1 (S363) Polyclonal Antibody
Product Synonym Names
OPRD1; OPRD; Delta-type opioid receptor; D-OR-1; DOR-1
Product Gene Name
anti-DOR-1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purified
Concentration
1mg/ml (lot specific)
Immunogen
Synthesized peptide derived from human DOR-1 around the phosphorylation site of S363.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-DOR-1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-DOR-1 antibody
Phospho Antibodies
Applications Tested/Suitable for anti-DOR-1 antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-DOR-1 antibody
WB: 1:500-1:2000, IHC: 1:50-1:200, ELISA: 1:5000-1:20000
Western Blot (WB) of anti-DOR-1 antibody
Western Blot analysis of 293T cells with Phospho-DOR-1 (Ser363) Polyclonal Antibody
NCBI/Uniprot data below describe general gene information for DOR-1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_000902.3
[Other Products]
NCBI GenBank Nucleotide #
NM_000911.3
[Other Products]
UniProt Secondary Accession #
B5B0B8[Other Products]
UniProt Related Accession #
P41143[Other Products]
Molecular Weight
Calculated MW: 40 kDa
NCBI Official Full Name
delta-type opioid receptor
NCBI Official Synonym Full Names
opioid receptor, delta 1
NCBI Official Symbol
OPRD1 [Similar Products]
NCBI Official Synonym Symbols
OPRD
[Similar Products]
NCBI Protein Information
delta-type opioid receptor
UniProt Protein Name
Delta-type opioid receptor
UniProt Gene Name
OPRD1 [Similar Products]
UniProt Synonym Gene Names
OPRD; D-OR-1; DOR-1 [Similar Products]
UniProt Entry Name
OPRD_HUMAN
UniProt Comments for DOR-1
DOR-1: delta opioid receptor, a G-protein coupled receptor. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Highly stereoselective. Receptor for enkephalins.
Protein type: Receptor, GPCR; GPCR, family 1; Membrane protein, multi-pass; Membrane protein, integral
Chromosomal Location of Human Ortholog: 1p36.1-p34.3
Cellular Component: cytoplasm; integral to plasma membrane; intrinsic to plasma membrane; lipid raft; nerve terminal; neuron projection; plasma membrane; postsynaptic membrane; vesicle
Molecular Function: neuropeptide binding; opioid receptor activity; protein binding
Biological Process: activation of CREB transcription factor; ***** locomotory behavior; eating behavior; G-protein coupled receptor protein signaling pathway; G-protein signaling, adenylate cyclase inhibiting pathway; G-protein signaling, coupled to cyclic nucleotide second messenger; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); immune response; negative regulation of protein oligomerization; neuropeptide signaling pathway; positive regulation of peptidyl-serine phosphorylation; protein import into nucleus, translocation; regulation of calcium ion transport; regulation of mitochondrial membrane potential; regulation of sensory perception of pain; synaptic transmission
Research Articles on DOR-1
1. We have established a delta opioid receptor-PKC-Nrf2 axis as a part of the mechanism underlying cytoprotection against hypoxia/reoxygenation injury
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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