Product Name
Glutamate-gated chloride channel (GluClalpha), Recombinant Protein
Full Product Name
Recombinant Drosophila melanogaster Glutamate-gated chloride channel (GluClalpha)
Product Gene Name
GluClalpha recombinant protein
[Similar Products]
Product Synonym Gene Name
GluCl[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
23-456aa; full length protein
Sequence
NNAKINFREK EKKVLDQILG AGKYDARIRP SGINGTDGPA IVRINLFVRS IMTISDIKME YSVQLTFREQ WTDERLKFDD IQGRLKYLTL TEANRVWMPD LFFSNEKEGH FHNIIMPNVY IRIFPNGSVL YSIRISLTLA CPMNLKLYPL DRQICSLRMA SYGWTTNDLV FLWKEGDPVQ VVKNLHLPRF TLEKFLTDYC NSKTNTGEYS CLKVDLLFKR EFSYYLIQIY IPCCMLVIVS WVSFWLDQGA VPARVSLGVT TLLTMATQTS GINASLPPVS YTKAIDVWTG VCLTFVFGAL LEFALVNYAS RSGSNKANMH KESMKKKRRD LEQASLDAAS DLLDTDSNAT FAMKPLVRHP GDPLALEKRL QCEVHMQAPK RPNCCKTWLS KFPTRQCSRS KRIDVISRIT FPLVFALFNL VYWSTYLFRE EEDE
3D Structure
ModBase 3D Structure for Q94900
Host
Cell Free Expression
Form/Format
Liquid containing glycerol
Species
Drosophila melanogaster (Fruit fly)
Storage Buffer
Tris-based buffer, 50% glycerol.
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of GluClalpha recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for GluClalpha recombinant protein
Transmembrane Protein
Application Notes for GluClalpha recombinant protein
This is a recombinant transmembrane protein expressed in a cell-free expression system.
NCBI/Uniprot data below describe general gene information for GluClalpha. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001014641.2
[Other Products]
NCBI GenBank Nucleotide #
NM_001014641.4
[Other Products]
UniProt Primary Accession #
Q94900
[Other Products]
UniProt Secondary Accession #
O77295; Q0Q0M3; Q2PDQ5; Q59DV9; Q8IN68; Q9GQ52; Q9GQ53; Q9VDU5[Other Products]
Molecular Weight
52,036 Da
NCBI Official Full Name
GluClalpha, isoform L
NCBI Official Symbol
GluClalpha [Similar Products]
NCBI Official Synonym Symbols
BcDNA:HL07853; CG7535; CT23049; dGluCl-alpha; Dm-GluCl; DmelCG7535; DmGlu; DmGluClalpha; DrosGlu-Cl-alpha; DrosGluCl; DrosGluCl-alpha; DrosGluCl-alpha1; glc; glu; GluCl; GLUCL; GluCla
[Similar Products]
NCBI Protein Information
CG7535 gene product from transcript CG7535-RK
UniProt Protein Name
Glutamate-gated chloride channel
Protein Family
Glutamate-gated chloride channel
UniProt Gene Name
GluClalpha [Similar Products]
UniProt Synonym Gene Names
; DrosGluCl [Similar Products]
UniProt Entry Name
GLUCL_DROME
UniProt Comments for GluClalpha
Glutamate-gated chloride channel subunit. Glutamate binding triggers a rapidly reversible current, while the anti-helmintic drug ivermectin triggers a permanently open channel configuration.
Research Articles on GluClalpha
1. Glutamate hyperpolarizes all major cell types in the antennal lobe, and this effect is blocked by picrotoxin or by transgenic RNAi-mediated knockdown of the GluClalpha gene, which encodes a glutamate-gated chloride channel.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
