Leber congenital amaurosis 5, ELISA Kit

Human Lebercilin (LCA5) ELISA kit; C6orf152; OTTHUMP00000165989; lebercilin; Leber congenital amaurosis 5

For Research Use Only. Not for use in diagnostic procedures.

No significant cross-reactivity or interference between this analyte and analogues is observed.

Store all reagents at 2-8 degree C

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.

Small volumes of LCA5 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9317249 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Leber congenital amaurosis 5 (LCA5) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing LCA5. The ELISA analytical biochemical technique of the MBS9317249 kit is based on LCA5 antibody-LCA5 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect LCA5 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, LCA5. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of LCA5 (hereafter termed this analyte) in undiluted original Human serum, plasma and tissue homogenate samples.

80,554 Da

Leber congenital amaurosis 5

Lebercilin; leber congenital amaurosis 5 protein

Lebercilin

C6orf152  [Similar Products]

LCA5_HUMAN

This gene encodes a protein that is thought to be involved in centrosomal or ciliary functions. Mutations in this gene cause Leber congenital amaurosis type V. Alternatively spliced transcript variants are described. [provided by RefSeq, Oct 2009]

LCA5: Might be involved in minus end-directed microtubule transport. Defects in LCA5 are the cause of Leber congenital amaurosis type 5 (LCA5). LCA designates a clinically and genetically heterogeneous group of childhood retinal degenerations, generally inherited in an autosomal recessive manner. Affected infants have little or no retinal photoreceptor function as tested by electroretinography. LCA represents the most common genetic cause of congenital visual impairment in infants and children. Belongs to the LCA5 family.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 6q14.1

Cellular Component: cytoplasm; microtubule organizing center; cilium

Molecular Function: protein binding; protein complex binding

Biological Process: protein transport; photoreceptor cell maintenance; intraflagellar transport

Disease: Leber Congenital Amaurosis 5

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