Product Name
TSPYL1, Polyclonal Antibody
Full Product Name
TSPYL1 Rabbit Polyclonal
Product Gene Name
anti-TSPYL1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Species Reactivity
Human, Mouse
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-TSPYL1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-TSPYL1 antibody
ELISA (EIA), Western Blot (WB)
NCBI/Uniprot data below describe general gene information for TSPYL1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_003300.1
[Other Products]
NCBI GenBank Nucleotide #
NM_003309.3
[Other Products]
UniProt Secondary Accession #
O75885; Q5TFE6[Other Products]
UniProt Related Accession #
Q9H0U9[Other Products]
Molecular Weight
49,192 Da
NCBI Official Full Name
testis-specific Y-encoded-like protein 1
NCBI Official Synonym Full Names
TSPY-like 1
NCBI Official Symbol
TSPYL1 [Similar Products]
NCBI Official Synonym Symbols
TSPYL
[Similar Products]
NCBI Protein Information
testis-specific Y-encoded-like protein 1
UniProt Protein Name
Testis-specific Y-encoded-like protein 1
Protein Family
Testis-specific Y-encoded-like protein
UniProt Gene Name
TSPYL1 [Similar Products]
UniProt Synonym Gene Names
TSPYL; TSPY-like protein 1 [Similar Products]
UniProt Entry Name
TSYL1_HUMAN
NCBI Summary for TSPYL1
The protein encoded by this gene is found in the nucleolus and is similar to that of a family of genes on the Y-chromosome. This gene is intronless. Defects in this gene are a cause of sudden infant death with dysgenesis of the testes syndrome (SIDDT). [provided by RefSeq, Dec 2009]
UniProt Comments for TSPYL1
TSPYL1: Defects in TSPYL1 are the cause of sudden infant death with dysgenesis of the testes syndrome (SIDDT). SIDDT is an autosomal recessive disorder. Affected infants appear normal at birth, develop signs of visceroautonomic dysfunction early in life, and die before 12 months of age of abrupt cardiorespiratory arrest. Features included bradycardia, hypothermia, severe gastroesophageal reflux, laryngospasm, bronchospasm, and abnormal cardiorespiratory patterns during sleep. Genotypic males with SIDDT had fetal testicular dysgenesis and ambiguous genitalia, with findings such as intraabdominal testes, dysplastic testes, deficient fetal testosterone production, fusion and rugation of the gonadal sac, and partial development of the penile shaft. Female sexual development was normal. Affected infants had an unusual staccato cry, similar to the cry of a goat. Belongs to the nucleosome assembly protein (NAP) family.
Protein type: Nucleolus
Chromosomal Location of Human Ortholog: 6q22.1
Cellular Component: nucleolus; nucleus
Molecular Function: enzyme binding
Biological Process: nucleosome assembly
Disease: Sudden Infant Death With Dysgenesis Of The Testes Syndrome
Research Articles on TSPYL1
1. Results show that mutations and polymorphisms in the TSPYL1 gene were not associated with sudden infant death syndrome in a cohort of 165 deceased Swiss infants.
Precautions
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Disclaimer
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