Product Name
3-hydroxyisobutyrate dehydrogenase, mitochondrial (HIBADH), Recombinant Protein
Full Product Name
Recombinant Human 3-hydroxyisobutyrate dehydrogenase, mitochondrial (HIBADH)
Product Gene Name
HIBADH recombinant protein
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
37-336aa, Full Length of Mature Protein
Sequence
ASKTPVGFIG LGNMGNPMAK NLMKHGYPLI IYDVFPDACK EFQDAGEQVV SSPADVAEKA DRIITMLPTS INAIEAYSGA NGILKKVKKG SLLIDSSTID PAVSKELAKE VEKMGAVFMD APVSGGVGAA RSGNLTFMVG GVEDEFAAAQ ELLGCMGSNV VYCGAVGTGQ AAKICNNMLL AISMIGTAEA MNLGIRLGLD PKLLAKILNM SSGRCWSSDT YNPVPGVMDG VPSANNYQGG FGTTLMAKDL GLAQDSATST KSPILLGSLA HQIYRMMCAK GYSKKDFSSV FQFLREEETF
3D Structure
ModBase 3D Structure for P31937
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of HIBADH recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for HIBADH. It may not necessarily be applicable to this product.
NCBI Accession #
NP_689953.1
[Other Products]
NCBI GenBank Nucleotide #
NM_152740.3
[Other Products]
UniProt Primary Accession #
P31937
[Other Products]
UniProt Secondary Accession #
Q546Z2; Q9UDN3[Other Products]
UniProt Related Accession #
P31937[Other Products]
Molecular Weight
35,329 Da
NCBI Official Full Name
3-hydroxyisobutyrate dehydrogenase, mitochondrial
NCBI Official Synonym Full Names
3-hydroxyisobutyrate dehydrogenase
NCBI Official Symbol
HIBADH [Similar Products]
NCBI Official Synonym Symbols
NS5ATP1
[Similar Products]
NCBI Protein Information
3-hydroxyisobutyrate dehydrogenase, mitochondrial
UniProt Protein Name
3-hydroxyisobutyrate dehydrogenase, mitochondrial
Protein Family
3-hydroxyisobutyrate dehydrogenase
UniProt Gene Name
HIBADH [Similar Products]
UniProt Synonym Gene Names
HIBADH [Similar Products]
NCBI Summary for HIBADH
This gene encodes a mitochondrial 3-hydroxyisobutyrate dehydrogenase enzyme. The encoded protein plays a critical role in the catabolism of L-valine by catalyzing the oxidation of 3-hydroxyisobutyrate to methylmalonate semialdehyde. [provided by RefSeq, Nov 2011]
Research Articles on HIBADH
1. HIBADH is involved in the mitochondrial function of spermatozoa, and maintains sperm motility. It may serve as a sperm-motility marker.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
