3-hydroxybutyrate dehydrogenase, type 1, Monoclonal Antibody

Anti -3-hydroxybutyrate dehydrogenase, type 1 (3-hydroxybutyrate dehydrogenase, BDH, BDH1, D-beta-hydroxybutyrate dehydrogenase, mitochondrial, MGC2723, MGC4347, MGC9788, SDR9C1)

For Research Use Only. Not for use in diagnostic procedures.

Chromosome: 3; NC_000003.11 (197236654..197300194, complement). Location: 3q29

Monoclonal

IgG1

10F603

Mouse

Recognizes human 3-hydroxybutyrate dehydrogenase, type 1 at 38kD. Species Crossreactivity: mouse.

Ascites
Ascites

Supplied as liquid, 0.04% sodium azide.

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Small volumes of anti-BDH1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

BDH1 (3-hydroxybutyrate dehydrogenase, type 1), it is a member of the short-chain dehydrogenase/reductase gene family. This protein forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific requirement for phosphatidylcholine for optimal enzymatic activity. It catalyzes the interconversion of acetoacetate and (R)-3-hydroxybutyrate, the two major ketone bodies produced during fatty acid catabolism.

Antibodies; Abs to Enzymes, Dehydrogenase

ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)

Suitable for use in ELISA, Western Blot and Immunohistochemistry.
Dilution: ELISA: 1:10,000
Western Blot: 1:500-1:2000
Immunohistochemistry (Paraffin): 1:200-1:1000

38,157 Da[Similar Products]

3-hydroxybutyrate dehydrogenase, type 1

D-beta-hydroxybutyrate dehydrogenase, mitochondrial; OTTHUMP00000208056; OTTHUMP00000208057; OTTHUMP00000208058; OTTHUMP00000208059; (R)-3-hydroxybutyrate dehydrogenase; 3-hydroxybutyrate dehydrogenase (heart, mitochondrial); short chain dehydrogenase/reductase family 9C, member 1

D-beta-hydroxybutyrate dehydrogenase, mitochondrial

BDH  [Similar Products]

BDH_HUMAN

This gene encodes a member of the short-chain dehydrogenase/reductase gene family. The encoded protein forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific requirement for phosphatidylcholine for optimal enzymatic activity. The encoded protein catalyzes the interconversion of acetoacetate and (R)-3-hydroxybutyrate, the two major ketone bodies produced during fatty acid catabolism. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq]

BDH: a member of the short-chain dehydrogenase/reductase gene family. The encoded protein forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific requirement for phosphatidylcholine for optimal enzymatic activity. The encoded protein catalyzes the interconversion of acetoacetate and (R)-3-hydroxybutyrate, the two major ketone bodies produced during fatty acid catabolism. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008]

Protein type: Mitochondrial; Lipid Metabolism - synthesis and degradation of ketone bodies; Oxidoreductase; EC 1.1.1.30; Carbohydrate Metabolism - butanoate

Chromosomal Location of Human Ortholog: 3q29

Cellular Component: nucleoplasm; mitochondrion; mitochondrial matrix; cytoplasm; mitochondrial inner membrane

Molecular Function: 3-hydroxybutyrate dehydrogenase activity; phospholipid binding

Biological Process: response to drug; response to toxin; ketone body metabolic process; cellular lipid metabolic process; liver development; response to estradiol stimulus; response to insulin stimulus; response to starvation; response to cadmium ion; response to ethanol; ketone body catabolic process; ketone body biosynthetic process; brain development; response to nutrient; response to corticosterone stimulus

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