Full Product Name
LIPB1 Antibody
Product Synonym Names
Liprin-beta-1; Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1; PTPRF-interacting protein-binding protein 1; hSGT2; PPFIBP1; KIAA1230
Product Gene Name
anti-LIPB1 antibody
[Similar Products]
Product Synonym Gene Name
PPFIBP1[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q86W92
Species Reactivity
Human, Mouse
Specificity
LIPB1 Antibody detects endogenous levels of LIPB1.
Purity/Purification
Purified from rabbit antiserum by affinity-chromatography using immunogen.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1 mg/ml (lot specific)
Target Modification
Unmodified/Total
Immunogen
The antiserum was produced against synthesized peptide derived from human LIPB1.
Preparation and Storage
Stable at -20 degree C for at least 1 year.
Other Notes
Small volumes of anti-LIPB1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-LIPB1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-LIPB1 antibody
WB: 1:500~1:1000
ELISA: 1:10000
NCBI/Uniprot data below describe general gene information for LIPB1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001185844.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001198915.1
[Other Products]
UniProt Primary Accession #
Q86W92
[Other Products]
UniProt Secondary Accession #
O75336; Q86X70; Q9NY03; Q9ULJ0[Other Products]
UniProt Related Accession #
Q86W92[Other Products]
NCBI Official Full Name
liprin-beta-1 isoform 3
NCBI Official Synonym Full Names
PPFIA binding protein 1
NCBI Official Symbol
PPFIBP1 [Similar Products]
NCBI Official Synonym Symbols
L2; SGT2; hSGT2; hSgt2p
[Similar Products]
NCBI Protein Information
liprin-beta-1
UniProt Protein Name
Liprin-beta-1
UniProt Synonym Protein Names
Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1; PTPRF-interacting protein-binding protein 1; hSGT2
Protein Family
Probable octanoyltransferase
UniProt Gene Name
PPFIBP1 [Similar Products]
UniProt Synonym Gene Names
KIAA1230; PTPRF-interacting protein-binding protein 1 [Similar Products]
NCBI Summary for LIPB1
The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis. In vitro experiment demonstrated that the interaction inhibited the phosphorylation of this protein by protein kinase C and protein kinase CK2. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
UniProt Comments for LIPB1
May regulate the disassembly of focal adhesions. Did not bind receptor-like tyrosine phosphatases type 2A.
Research Articles on LIPB1
1. liprin beta-1 is associated with expression of kank 1 and 2 proteins in melanoma
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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