Full Product Name
GPC5 Antibody
Product Gene Name
anti-GPC5 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P78333
Specificity
The antibody detects endogenous levels of total GPC5 protein.
Purity/Purification
Antigen affinity purification
Form/Format
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Concentration
1.1mg/ml (lot specific)
Immunogen
Synthetic peptide of human GPC5
Preparation and Storage
Store at -20 degree C
Other Notes
Small volumes of anti-GPC5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-GPC5 antibody
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation.
Product Categories/Family for anti-GPC5 antibody
Total protein Ab
Applications Tested/Suitable for anti-GPC5 antibody
Immunohistochemistry (IHC)
Application Notes for anti-GPC5 antibody
Immunohistochemistry: 1: 30-150
Immunohistochemistry (IHC) of anti-GPC5 antibody
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using GPC5 Antibody at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200)
NCBI/Uniprot data below describe general gene information for GPC5. It may not necessarily be applicable to this product.
NCBI Accession #
NP_004457.1
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NCBI GenBank Nucleotide #
NM_004466.5
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UniProt Primary Accession #
P78333
[Other Products]
UniProt Secondary Accession #
O60436; Q9BX27; B2R726[Other Products]
UniProt Related Accession #
P78333[Other Products]
Molecular Weight
63,707 Da
NCBI Official Full Name
glypican-5
NCBI Official Synonym Full Names
glypican 5
NCBI Official Symbol
GPC5 [Similar Products]
NCBI Protein Information
glypican-5
UniProt Protein Name
Glypican-5
UniProt Gene Name
GPC5 [Similar Products]
UniProt Entry Name
GPC5_HUMAN
NCBI Summary for GPC5
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. [provided by RefSeq, Jul 2008]
UniProt Comments for GPC5
GPC5: Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
Protein type: Cell surface; Membrane protein, GPI anchor; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 13q32
Cellular Component: extracellular region; Golgi lumen; integral to plasma membrane; lysosomal lumen; plasma membrane
Biological Process: glycosaminoglycan biosynthetic process; glycosaminoglycan catabolic process; glycosaminoglycan metabolic process; retinoid metabolic process
Research Articles on GPC5
1. Results suggest a potential association between CRP and GPC5 variants with lung cancer risk; variation in GKN1 is associated with chemotherapy response in the Chinese Han population.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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