Product Name
KIAA0854 (ZHX2), Polyclonal Antibody
Full Product Name
KIAA0854 (Zinc Fingers and Homeoboxes Protein 2)
Product Synonym Names
Anti -KIAA0854 (Zinc Fingers and Homeoboxes Protein 2)
Product Gene Name
anti-ZHX2 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Chromosome Location
Chromosome: 8; NC_000008.10 (123793901..123986755). Location: 8q24.13
3D Structure
ModBase 3D Structure for Q9Y6X8
Species Reactivity
Human, Rodent
Specificity
Recognizes human KIAA0854. Species Crossreactivity: rodent.
Purity/Purification
Affinity Purified
Purified by Affinity chromatography.
Form/Format
Supplied as a liquid in PBS, sodium azide, before the addition of glycerol to 40%.
Immunogen
Synthetic peptide VANPPLTPASDRKKTKE corresponding to human KIAA0854 (KLH).
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Other Notes
Small volumes of anti-ZHX2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-ZHX2 antibody
Antibodies; Abs to Transcription Factors, Homeobox (HOX)
Applications Tested/Suitable for anti-ZHX2 antibody
ELISA (EL/EIA), Immunohistochemistry (IHC)
Application Notes for anti-ZHX2 antibody
Suitable for use in ELISA and Immunohistochemistry.
Dilution: ELISA (titer): 1:250,000.
Immunohistochemistry: 10ug/ml
NCBI/Uniprot data below describe general gene information for ZHX2. It may not necessarily be applicable to this product.
UniProt Primary Accession #
Q9Y6X8
[Other Products]
UniProt Related Accession #
Q9Y6X8[Other Products]
Molecular Weight
92.31kD.[Similar Products]
NCBI Official Full Name
KIAA0854 protein
NCBI Official Synonym Full Names
zinc fingers and homeoboxes 2
NCBI Official Symbol
ZHX2 [Similar Products]
NCBI Official Synonym Symbols
RAF; AFR1; KIAA0854
[Similar Products]
NCBI Protein Information
zinc fingers and homeoboxes protein 2; AFP regulator 1; regulator of AFP; OTTHUMP00000228361; transcription factor ZHX2; alpha-fetoprotein regulator 1; zinc-fingers and homeoboxes 2; zinc finger and homeodomain protein 2
UniProt Protein Name
Zinc fingers and homeoboxes protein 2
UniProt Synonym Protein Names
Alpha-fetoprotein regulator 1; AFP regulator 1; Regulator of AFP; Zinc finger and homeodomain protein 2
Protein Family
Zinc fingers and homeoboxes protein
UniProt Gene Name
ZHX2 [Similar Products]
UniProt Synonym Gene Names
AFR1; KIAA0854; RAF [Similar Products]
UniProt Entry Name
ZHX2_HUMAN
NCBI Summary for ZHX2
The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This gene encodes member 2 of this gene family. In addition to forming homodimers, this protein heterodimerizes with member 1 of the zinc fingers and homeoboxes family. [provided by RefSeq]
UniProt Comments for ZHX2
ZHX2: Acts as a transcriptional repressor. Represses the promoter activity of the CDC25C gene stimulated by NFYA. Belongs to the ZHX family.
Protein type: Transcription factor; DNA-binding; C2H2-type zinc finger protein
Chromosomal Location of Human Ortholog: 8q24.13
Cellular Component: nucleoplasm; cytoplasm; plasma membrane; nucleus
Molecular Function: identical protein binding; protein binding; protein homodimerization activity; DNA binding; protein heterodimerization activity; metal ion binding; transcription corepressor activity; transcription factor activity
Biological Process: negative regulation of neuron differentiation; transcription, DNA-dependent; somatic stem cell maintenance; mRNA catabolic process; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent
Research Articles on ZHX2
1. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
