Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (ASZ1)

ankyrin repeat, SAM and basic leucine zipper domain containing 1; ALP1; ANKL1; C7orf7; CT1.19; GASZ; MGC26634; Orf3; 4933400N19Rik|ankyrin-like 1

For Research Use Only. Not for use in diagnostic procedures.

Chromosome: A2; NC_018724.1 (135709165..135760449, complement). Location: chromosome: A2

Store all reagents at 2-8 degree C

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Small volumes of ASZ1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9330342 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (ASZ1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ASZ1. The ELISA analytical biochemical technique of the MBS9330342 kit is based on ASZ1 antibody-ASZ1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ASZ1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ASZ1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

53,184 Da

ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1; germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein

Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1

GASZ  [Similar Products]

ASZ1_FELCA

Function: Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation

By similarity.

Subunit structure: Interacts with DDX4, PIWIL1, RANBP9 and TDRD1

By similarity.

Subcellular location: Cytoplasm

By similarity. Note: Component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon during meiosis. Specifically localizes to pi-bodies, a subset of the nuage which contains primary piRNAs

By similarity.

Sequence similarities: Contains 6 ANK repeats.Contains 1 SAM (sterile alpha motif) domain.

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