A Disintegrin Like and Metalloproteinase With Thrombospondin Type 1 Motif 7, EL

For Research Use Only. Not for use in diagnostic procedures.

Chromosome: 15; NC_000015.9 (79051545..79103773, complement). Location: 15q24.2

Store all reagents at 2-8 degree C

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Small volumes of ADAMTS7 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS042197 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the A Disintegrin Like and Metalloproteinase With Thrombospondin Type 1 Motif 7 (ADAMTS7) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ADAMTS7. The ELISA analytical biochemical technique of the MBS042197 kit is based on ADAMTS7 antibody-ADAMTS7 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ADAMTS7 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ADAMTS7. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

184,095 Da

ADAM metallopeptidase with thrombospondin type 1 motif, 7

A disintegrin and metalloproteinase with thrombospondin motifs 7; COMPase; a disintegrin and metalloprotease with thrombospondin motifs-7 preproprotein; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 7

A disintegrin and metalloproteinase with thrombospondin motifs 7

ADAM-TS 7; ADAM-TS7; ADAMTS-7  [Similar Products]

ATS7_HUMAN

The protein encoded by this gene is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family. Members of this family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene contains two C-terminal TS motifs. [provided by RefSeq, Jul 2008]

ADAMTS7: Metalloprotease that may play a role in the degradation of COMP.

Protein type: EC 3.4.24.-; Secreted; Cell surface; Motility/polarity/chemotaxis; Protease; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 15q24.2

Cellular Component: proteinaceous extracellular matrix; cell surface; endoplasmic reticulum lumen

Molecular Function: protein binding; metallopeptidase activity; zinc ion binding; metalloendopeptidase activity

Biological Process: protein amino acid O-linked glycosylation; cellular protein metabolic process; proteolysis involved in cellular protein catabolic process; negative regulation of chondrocyte differentiation; post-translational protein modification

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