Product Name
Thromboxane A2 receptor (Tbxa2r), Recombinant Protein
Full Product Name
Recombinant Rat Thromboxane A2 receptor (Tbxa2r), partial
Product Gene Name
Tbxa2r recombinant protein
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P34978
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Rattus norvegicus (Rat)
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Tbxa2r recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for Tbxa2r. It may not necessarily be applicable to this product.
NCBI Accession #
NP_058750.1
[Other Products]
NCBI GenBank Nucleotide #
NM_017054.1
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UniProt Primary Accession #
P34978
[Other Products]
UniProt Related Accession #
P34978[Other Products]
Molecular Weight
36,928 Da
NCBI Official Full Name
thromboxane A2 receptor
NCBI Official Synonym Full Names
thromboxane A2 receptor
NCBI Official Symbol
Tbxa2r [Similar Products]
NCBI Protein Information
thromboxane A2 receptor
UniProt Protein Name
Thromboxane A2 receptor
UniProt Synonym Protein Names
Prostanoid TP receptor; TXR2
Protein Family
Thromboxane A2 receptor
UniProt Gene Name
Tbxa2r [Similar Products]
UniProt Synonym Gene Names
TXA2-R [Similar Products]
NCBI Summary for Tbxa2r
binds thromboxane and induces an increase in cytosolic Ca2+ levels; may play a role renal electrolyte metabolism; may mediate vascular smooth muscle cell contraction and proliferation [RGD, Feb 2006]
UniProt Comments for Tbxa2r
Receptor for thromboxane A2 (TXA2), a potent stimulator of platelet aggregation. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system. In the kidney, the binding of TXA2 to glomerular TP receptors causes intense vasoconstriction. Activates phospholipase C and adenylyl cyclase.
Research Articles on Tbxa2r
1. the long-lasting oligemia following cortical spreading depression consists of at least two distinct temporal phases, mediated by preferential actions of COX-1- and COX-2-derived prostanoids: an initial phase mediated by COX-1 that involves TXA2 followed by a later phase, mediated by COX-2 and PGF2alpha.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
