Full Product Name
RGS9 Antibody
Product Synonym Names
RGS9; PERRS; RGS9L
Product Gene Name
anti-RGS9 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for O75916
Species Reactivity
Human, Mouse
Specificity
RGS9 Antibody detects endogenous levels of total RGS9
Form/Format
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0mg/mL (lot specific)
Immunogen
A synthesized peptide derived from human RGS9
Preparation and Storage
Store at -20 degree C
Other Notes
Small volumes of anti-RGS9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-RGS9 antibody
Total protein Ab
Applications Tested/Suitable for anti-RGS9 antibody
Western Blot (WB)
Application Notes for anti-RGS9 antibody
Western Blot: 1:1000-3000
Western Blot (WB) of anti-RGS9 antibody
Western blot analysis RGS9 using K562 whole cell lysates
NCBI/Uniprot data below describe general gene information for RGS9. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001075424.1
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NCBI GenBank Nucleotide #
NM_001081955.2
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UniProt Primary Accession #
O75916
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UniProt Secondary Accession #
O75573; Q696R2; Q8TD64; Q8TD65; Q9HC32; Q9HC33; A8K3C0[Other Products]
UniProt Related Accession #
O75916[Other Products]
Molecular Weight
76,625 Da
NCBI Official Full Name
regulator of G-protein signaling 9 isoform 2
NCBI Official Synonym Full Names
regulator of G-protein signaling 9
NCBI Official Symbol
RGS9 [Similar Products]
NCBI Official Synonym Symbols
PERRS; RGS9L
[Similar Products]
NCBI Protein Information
regulator of G-protein signaling 9
UniProt Protein Name
Regulator of G-protein signaling 9
Protein Family
Regulator of G-protein signaling
UniProt Gene Name
RGS9 [Similar Products]
UniProt Synonym Gene Names
RGS9 [Similar Products]
UniProt Entry Name
RGS9_HUMAN
NCBI Summary for RGS9
This gene encodes a member of the RGS family of GTPase activating proteins that function in various signaling pathways by accelerating the deactivation of G proteins. This protein is anchored to photoreceptor membranes in retinal cells and deactivates G proteins in the rod and cone phototransduction cascades. Mutations in this gene result in bradyopsia. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
UniProt Comments for RGS9
RGS9: belongs to the 'regulator of G protein signaling' family. Inhibits signal transduction by increasing the GTPAse activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(t)-alpha. Involved in phototransduction; key element in the recovery phase of visual transduction. Four alternatively spliced isoforms have been described.
Protein type: GAPs; GAPs, RGS
Chromosomal Location of Human Ortholog: 17q24
Cellular Component: cytoplasm; plasma membrane
Biological Process: protein folding
Disease: Prolonged Electroretinal Response Suppression
Research Articles on RGS9
1. To identify single-nucleotide polymorphisms that contribute to the genetic susceptibility to schizophrenia, we examined the potential association between schizophrenia and 9 single nucleotide polymorphisms in the G-protein signaling 9 gene
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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