Mannan-binding lectin serine protease 2, ELISA Kit

Mannan-binding lectin serine protease 2; MBL-associated serine protease 2; Mannose-binding protein-associated serine protease 2; MASP-2; Masp2; 3.4.21.104

For Research Use Only. Not for use in diagnostic procedures.

For long term storage, please store the entire kit at -20 degree C.

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.

Small volumes of Masp2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS2886277 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Mannan-binding lectin serine protease 2 (Masp2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing Masp2. The ELISA analytical biochemical technique of the MBS2886277 kit is based on Masp2 antibody-Masp2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Masp2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, Masp2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

20,974 Da

mannan-binding lectin serine peptidase 2

mannan-binding lectin serine protease 2

Mannan-binding lectin serine protease 2

MASP-2  [Similar Products]

MASP2_MOUSE

MASP2: Serum protease that plays an important role in the activation of the complement system via mannose-binding lectin. After activation by auto-catalytic cleavage it cleaves C2 and C4, leading to their activation and to the formation of C3 convertase. Defects in MASP2 are the cause of MASP2 deficiency (MASPD). MASPD is a disorder that results in autoimmune manifestations, recurrent severe infections, and chronic inflammatory disease. Belongs to the peptidase S1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; EC 3.4.21.104; Secreted; Protease

Cellular Component: extracellular region

Molecular Function: calcium ion binding; calcium-dependent protein binding; complement component C4b binding; hydrolase activity; metal ion binding; peptidase activity; protein binding; serine-type endopeptidase activity; serine-type peptidase activity

Biological Process: complement activation; complement activation, classical pathway; complement activation, lectin pathway; immune system process; innate immune response; proteolysis

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