Full Product Name
Anti-RAC2 Antibody
Product Gene Name
anti-RAC2 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P15153
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Affinity Purification
Concentration
1mg/ml (lot specific)
Immunogen
Recombinant protein of human RAC2
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Other Notes
Small volumes of anti-RAC2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-RAC2 antibody
Rac and Cdc42 are members of the Rho-GTPase family. In mammals, Rac exists as three isoforms, Rac1, Rac2 and Rac3, which are highly similar in sequence. Rac1 and Cdc42, the most widely studied of this group, are ubiquitously expressed.
Applications Tested/Suitable for anti-RAC2 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-RAC2 antibody
WB: 1:500-1:2000
IHC: 1:50-1:200
NCBI/Uniprot data below describe general gene information for RAC2. It may not necessarily be applicable to this product.
NCBI Accession #
CAG30441.1
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UniProt Primary Accession #
P15153
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UniProt Related Accession #
P15153[Other Products]
NCBI Official Full Name
RAC2
NCBI Official Synonym Full Names
Rac family small GTPase 2
NCBI Official Symbol
RAC2 [Similar Products]
NCBI Official Synonym Symbols
Gx; EN-7; HSPC022; p21-Rac2
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NCBI Protein Information
ras-related C3 botulinum toxin substrate 2
Protein Family
Ras-related protein
NCBI Summary for RAC2
This gene encodes a member of the Ras superfamily of small guanosine triphosphate (GTP)-metabolizing proteins. The encoded protein localizes to the plasma membrane, where it regulates diverse processes, such as secretion, phagocytosis, and cell polarization. Activity of this protein is also involved in the generation of reactive oxygen species. Mutations in this gene are associated with neutrophil immunodeficiency syndrome. There is a pseudogene for this gene on chromosome 6. [provided by RefSeq, Jul 2013]
Research Articles on RAC2
1. We found both the rs229527 allele within C1QTNF6 (odds ratio [OR] = 1.23, confidence interval [95% CI]: 1.12-1.33, pAllelic = 4.60 . 10-6) and the rs2284038 allele within RAC2 (OR = 1.10, 95% CI: 1.01-0.19, pAllelic = 3.00 . 10-2) showed significant associations with Graves' Disease susceptibility.
Precautions
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Disclaimer
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