Full Product Name
ZEB2 Antibody
Product Gene Name
anti-ZEB2 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for O60315
Other Notes
Small volumes of anti-ZEB2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for ZEB2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001165124.1
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NCBI GenBank Nucleotide #
NM_001171653.1
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UniProt Primary Accession #
O60315
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UniProt Secondary Accession #
Q9UED1; A0JP09; B7Z2P2; F5H814[Other Products]
UniProt Related Accession #
O60315[Other Products]
Molecular Weight
133,806 Da
NCBI Official Full Name
zinc finger E-box-binding homeobox 2 isoform 2
NCBI Official Synonym Full Names
zinc finger E-box binding homeobox 2
NCBI Official Symbol
ZEB2 [Similar Products]
NCBI Official Synonym Symbols
SIP1; SIP-1; ZFHX1B; HSPC082; SMADIP1
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NCBI Protein Information
zinc finger E-box-binding homeobox 2
UniProt Protein Name
Zinc finger E-box-binding homeobox 2
UniProt Synonym Protein Names
Smad-interacting protein 1; SMADIP1; Zinc finger homeobox protein 1b
Protein Family
Zinc finger E-box-binding homeobox
UniProt Gene Name
ZEB2 [Similar Products]
UniProt Synonym Gene Names
KIAA0569; SIP1; ZFHX1B; ZFX1B; SMADIP1 [Similar Products]
NCBI Summary for ZEB2
The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Mutations in this gene are associated with Hirschsprung disease/Mowat-Wilson syndrome. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jan 2010]
UniProt Comments for ZEB2
Transcriptional inhibitor that binds to DNA sequence 5'-CACCT-3' in different promoters. Represses transcription of E-cadherin.
Research Articles on ZEB2
1. Our study confirms that the two susceptibility loci ZFHX1B and SNTB1 are associated with moderate to high myopia in a Han Chinese population, as well as in a European population, when both SNPs are combined.
Precautions
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Disclaimer
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