Product Name
CD102 (ICAM2), Blocking Peptide
Popular Item
Full Product Name
CD102 Blocking Peptide
Product Synonym Names
Intercellular adhesion molecule 2; ICAM-2; CD102
Product Gene Name
ICAM2 blocking peptide
[Similar Products]
CD102 peptide (MBS823225) is used for blocking the activity of CD102 antibody (MBS820389)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P13598
Species Reactivity
Human, Mouse, Rat
Form/Format
Lyophilized powder
Quality Control
The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.
Preparation and Storage
Ships on blue ice. Store at -20 degree C for one year.
Other Notes
Small volumes of ICAM2 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
ICAM2 blocking peptide
The peptide is used to block Anti-CD102 Antibody reactivity.
Applications Tested/Suitable for ICAM2 blocking peptide
Blocking (BL)
Application Notes for ICAM2 blocking peptide
Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours.
NCBI/Uniprot data below describe general gene information for ICAM2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_000864.2
[Other Products]
NCBI GenBank Nucleotide #
NM_000873.3
[Other Products]
UniProt Primary Accession #
P13598
[Other Products]
UniProt Secondary Accession #
Q14600[Other Products]
UniProt Related Accession #
P13598[Other Products]
NCBI Official Full Name
intercellular adhesion molecule 2
NCBI Official Synonym Full Names
intercellular adhesion molecule 2
NCBI Official Symbol
ICAM2 [Similar Products]
NCBI Official Synonym Symbols
CD102
[Similar Products]
NCBI Protein Information
intercellular adhesion molecule 2; ICAM-2
UniProt Protein Name
Intercellular adhesion molecule 2
UniProt Synonym Protein Names
CD_antigen: CD102
Protein Family
Intercellular adhesion molecule
UniProt Gene Name
ICAM2 [Similar Products]
UniProt Synonym Gene Names
ICAM-2 [Similar Products]
UniProt Entry Name
ICAM2_HUMAN
NCBI Summary for ICAM2
The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for ICAM2
ICAM2: ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen- specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Belongs to the immunoglobulin superfamily. ICAM family.
Protein type: Membrane protein, integral; Cell adhesion
Chromosomal Location of Human Ortholog: 17q23.3
Cellular Component: membrane; integral to plasma membrane; plasma membrane; uropod
Molecular Function: integrin binding
Biological Process: cell-cell adhesion; extracellular matrix organization and biogenesis; regulation of immune response; cell adhesion
Research Articles on ICAM2
1. with larger patient groups and preferably detailed histopathological and clinical evaluations, are needed to explain the severity of ICAM-1, ICAM-2, and ICAM-3 molecules in Barrett's esophagus
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
