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Glycine Receptor Alpha 2 (GLRa2), Antibody Pair Kit

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产品名称: Glycine Receptor Alpha 2 (GLRa2), Antibody Pair Kit
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简单介绍

Glycine Receptor Alpha 2 (GLRa2), Antibody Pair Kit


Glycine Receptor Alpha 2 (GLRa2), Antibody Pair Kit  的详细介绍
Product Name

Glycine Receptor Alpha 2 (GLRa2), Antibody Pair Kit

Full Product Name

Glycine Receptor Alpha 2 (GLRa2) Antibody Pair Kit (with Standard)

Product Synonym Names
GLR
Product Gene Name

GLRa2 antibody pair kit

[Similar Products]
Matching Pairs
Antibody: Glycine Receptor Alpha 2 (GLRa2) (MBS2103217)
Pairing: Glycine Receptor Alpha 2 (GLRa2) (MBS2103217)
Comments: Matched antibody pair kit containing antibody/standard combination
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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Request for Current Manual Insert
Request Current Manual
OMIM
X52008 mRNA
Species Reactivity
Rat
Samples
Tissue Homogenates, Cell Lysates and Other Biological Fluids
Detection Range
0.625-40ng/mL
Standard
Recombinant GLRa2 (Lyophilized, 1 vial-10ug)
Capture Antibody
Rabbit polyclonal antibody (Liquid, 1 vial-400mug/800muL)
Detection Antibody
Biotinylated Rabbit polyclonal antibody (Liquid, 1 vial-100mug/500muL)
Producte Usage
Raw materials can be used for preparation of 5x96T or 10x96T ELISA Kits.
Antibody Support Pack
Antibody Support Pack (Buffer Pack) is sold separately as catalog #MBS2090685
ISO Certification
Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of GLRa2 antibody pair kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Categories/Family for GLRa2 antibody pair kit
Neuro science
Applications Tested/Suitable for GLRa2 antibody pair kit
ELISA (EIA), Chemiluminescence Immunoassays (CLIA), ELISPOT, Luminex
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NCBI/Uniprot data below describe general gene information for GLRa2. It may not necessarily be applicable to this product.
NCBI GI #
3598701
NCBI GeneID
2742
NCBI Accession #
AAC35290.1 [Other Products]
UniProt Secondary Accession #
Q53YX7; Q6ICQ0; Q99862; A8K0J6; B2R6I8; B7Z4F5; J3KQ59[Other Products]
UniProt Related Accession #
P23416[Other Products]
Molecular Weight
42,002 Da
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NCBI Official Full Name
glycine receptor alpha 2 subunit
NCBI Official Synonym Full Names
glycine receptor alpha 2
NCBI Official Symbol
GLRA2  [Similar Products]
NCBI Official Synonym Symbols
GLR
  [Similar Products]
NCBI Protein Information
glycine receptor subunit alpha-2
UniProt Protein Name
Glycine receptor subunit alpha-2
Protein Family
Glycine receptor
UniProt Gene Name
GLRA2  [Similar Products]
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NCBI Summary for GLRa2
The glycine receptor consists of two subunits, alpha and beta, and acts as a pentamer. The protein encoded by this gene is an alpha subunit and can bind strychnine. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2010]
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UniProt Comments for GLRa2
Glycine receptors are ligand-gated chloride channels. Channel opening is triggered by extracellular glycine (PubMed:2155780, PubMed:15302677, PubMed:16144831, PubMed:23895467, PubMed:25445488). Channel opening is also triggered by taurine and beta-alanine (PubMed:15302677). Plays a role in the down-regulation of neuronal excitability. Contributes to the generation of inhibitory postsynaptic currents (PubMed:25445488). Plays a role in cellular responses to ethanol (PubMed:23895467).
Research Articles on GLRa2
1. data show that the current-voltage relationships of homomeric channels formed by the alpha2 or alpha3 subunits change upon receptor desensitization from a linear to an inwardly rectifying shape, in contrast to their heteromeric counterparts.
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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