Full Product Name
trp Antibody BIOTIN-Conjugated
Product Synonym Names
DmTRP; dTRP; Transient receptor potential antibody
Product Gene Name
anti-trp antibody
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Matching Pairs
Antibody: trp (MBS5400175)
Positive Control: trp (MBS543354)
Antibody/Peptide Pairs
trp peptide (MBS544619) is used for blocking the activity of trp antibody (MBS5400175)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P19334
Species Reactivity
Drosophila melanogaster
Form/Format
BIOTIN-Conjugated
Concentration
0.62 ug/ul in antibody stabilization buffer (lot specific)
Immunogen
Synthetic peptide corresponding to unique amino acid sequences on D. melanogaster Transient Receptor Potential isoform A protein.
Expression
Expressed predominantly in the rhabdomeres of photoreceptor cells. Expressed in the third antennal segment and in the olfactory segment at approximately 70 hours after puparium formation during antennal development.
Molecular Function
Calcium channel, Ion channel, Calmodulin activity
Structure
The C-terminus interacts with a PDZ domain of inaD to form the core of the inaD signaling complex. Other members of the complex include norpA (PLC), inaC (PKC), and possibly trpl, ninaC, FKBP59, calmodulin and rhodopsin. Forms homomultimers and heteromult
Subcellular Location
Cell membrane; Multi-pass membrane protein
Preparation and Storage
-20 degree C for long term storage
Other Notes
Small volumes of anti-trp antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-trp antibody
BIOTIN-Conjugated Transient Receptor Potential isoform A Antibody
A light-sensitive calcium channel that is required for inositide-mediated Ca2+ entry in the retina during phospholipase C (PLC)-mediated phototransduction. Ca2+ influx may then feed back and inhibit PLC, thereby facilitating phosphatidylinositol 4, 5 bisphosphate (PIP2) recycling.
Applications Tested/Suitable for anti-trp antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-trp antibody
Dot Blot: 1:10,000
ELISA: 1:10,000
Western Blot: 1:10,000
NCBI/Uniprot data below describe general gene information for trp. It may not necessarily be applicable to this product.
NCBI Accession #
NP_476768.1
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NCBI GenBank Nucleotide #
NM_057420.4
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UniProt Primary Accession #
P19334
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UniProt Secondary Accession #
Q7YU76; Q9VAE1[Other Products]
UniProt Related Accession #
P19334[Other Products]
Molecular Weight
142,594 Da
NCBI Official Full Name
transient receptor potential, isoform A
NCBI Official Synonym Full Names
transient receptor potential
NCBI Official Symbol
trp [Similar Products]
NCBI Official Synonym Symbols
559; CG7875; DmelCG7875; DmTRP; dTrp; dTRP; gene B; idl-B; Trp; TRP
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NCBI Protein Information
CG7875 gene product from transcript CG7875-RA
UniProt Protein Name
Transient receptor potential protein
Protein Family
Trp-Contryphan
UniProt Gene Name
trp [Similar Products]
UniProt Entry Name
TRP_DROME
UniProt Comments for trp
A light-sensitive calcium channel that is required for inositide-mediated Ca2+ entry in the retina during phospholipase C (PLC)-mediated phototransduction. Ca2+ influx may then feed back and inhibit PLC, thereby facilitating phosphatidylinositol 4,5 bisphosphate (PIP2) recycling. Trp and trpl act together in the light response, though it is unclear whether as heteromultimers or as distinct units, and are activated by fatty acids and metabolic stress. Also required for olfactory adaptation and may be involved in olfactory system development.
Research Articles on trp
1. Data show that phosphorylation of most ransient receptor potential (TRP) ion channel sites depends on the phototransduction cascade and the activity of the TRP.
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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