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Killer cell lectin-like receptor subfamily G member 1 (Klrg1), Recombinant Prot

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产品名称: Killer cell lectin-like receptor subfamily G member 1 (Klrg1), Recombinant Prot
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简单介绍

Killer cell lectin-like receptor subfamily G member 1 (Klrg1), Recombinant Protein


Killer cell lectin-like receptor subfamily G member 1 (Klrg1), Recombinant Prot  的详细介绍
Product Name

Killer cell lectin-like receptor subfamily G member 1 (Klrg1), Recombinant Protein

Full Product Name

Recombinant Rat Killer cell lectin-like receptor subfamily G member 1 (Klrg1), partial

Product Gene Name

Klrg1 recombinant protein

[Similar Products]
Product Synonym Gene Name
Klrg1[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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Sequence Positions
56-188
Sequence
YQRTL CCGSKGFMCS QCSRCPNLWM RNGSHCYYFS MEKRDWNSSL KFCADKGSHL LTFPDNQGVN LFQEYVGEDF YWIGLRDIDG WRWEDGPALS LSILSNSVVQ KCGTIHRCGL HASSCEVALQ WICEKVLP
3D Structure
ModBase 3D Structure for Q64335
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Rat
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Klrg1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for
Klrg1 recombinant protein
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. This protein belongs to the killer cell lectin-like receptor (KLR) family, which is a group of transmembrane proteins preferentially expressed in NK cells. Studies in mice suggested that the expression of this gene may be regulated by MHC class I molecules. Alternatively spliced transcript variants have been reported, but their full-length natures have not yet been determined.
NCBI/Uniprot data below describe general gene information for Klrg1. It may not necessarily be applicable to this product.
NCBI GI #
13928898
NCBI GeneID
58975
NCBI Accession #
NP_113837.1 [Other Products]
NCBI GenBank Nucleotide #
NM_031649.2 [Other Products]
UniProt Primary Accession #
Q64335 [Other Products]
UniProt Related Accession #
Q64335[Other Products]
Molecular Weight
21,356 Da
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NCBI Official Full Name
killer cell lectin-like receptor subfamily G member 1
NCBI Official Synonym Full Names
killer cell lectin like receptor G1
NCBI Official Symbol
Klrg1  [Similar Products]
NCBI Official Synonym Symbols
MAFA
  [Similar Products]
NCBI Protein Information
killer cell lectin-like receptor subfamily G member 1
UniProt Protein Name
Killer cell lectin-like receptor subfamily G member 1
UniProt Synonym Protein Names
Mast cell function-associated antigen
Protein Family
Killer cell lectin-like receptor subfamily
UniProt Gene Name
Klrg1  [Similar Products]
UniProt Synonym Gene Names
Mafa  [Similar Products]
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NCBI Summary for Klrg1
a membrane glycoprotein that interferes with the coupling cascade of the type 1 Fc epsilon receptor induced mast cell secretory response [RGD, Feb 2006]
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UniProt Comments for Klrg1
Plays an inhibitory role on natural killer (NK) cells and T-cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E-cadherin/CDH1, N-cadherin/CDH2 and R-cadherin/CDH4 on target cells ().
Research Articles on Klrg1
1. a key role of PPARgamma in regulating pancreatic beta-cell function by improving the stability of Pdx1 and Mafa proteins
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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