Full Product Name
HADH Antibody
Product Synonym Names
HADH; HAD; HADH1; HADHSC; HHF4; M/SCHAD; MGC8392; SCHAD
Product Gene Name
anti-HADH antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q16836
Species Reactivity
Human, Mouse
Specificity
HADH Antibody detects endogenous levels of total HADH
Purity/Purification
Immunogen affinity purified
Form/Format
In phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen
Recombinant protein of human HADH
Preparation and Storage
Store at-20 degree C for 1 year
Other Notes
Small volumes of anti-HADH antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-HADH antibody
This gene is a member of the 3-hydroxyacyl-CoA dehydrogenase gene family. The encoded protein functions in the mitochondrial matrix to catalyze the oxidation of straight-chain 3-hydroxyacyl-CoAs as part of the beta-oxidation pathway.
Applications Tested/Suitable for anti-HADH antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-HADH antibody
WB: 1:500-1:2000
IHC: 1:50-1:200
Western Blot (WB) of anti-HADH antibody
Western blot analysis of extracts of variouscell lines, using HADH antibody.
NCBI/Uniprot data below describe general gene information for HADH. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001171634.2
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NCBI GenBank Nucleotide #
NM_001184705.2
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UniProt Primary Accession #
Q16836
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UniProt Secondary Accession #
O00324; O00397; O00753; Q4W5B4; J3KQ17[Other Products]
UniProt Related Accession #
Q16836[Other Products]
NCBI Official Full Name
hydroxyacyl-coenzyme A dehydrogenase, mitochondrial isoform 1
NCBI Official Synonym Full Names
hydroxyacyl-CoA dehydrogenase
NCBI Official Symbol
HADH [Similar Products]
NCBI Official Synonym Symbols
HAD; HCDH; HHF4; HADH1; SCHAD; HADHSC; MSCHAD
[Similar Products]
NCBI Protein Information
hydroxyacyl-coenzyme A dehydrogenase, mitochondrial
UniProt Protein Name
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial
UniProt Synonym Protein Names
Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase; Short-chain 3-hydroxyacyl-CoA dehydrogenase
Protein Family
Hydroxyacyl-coenzyme A dehydrogenase
UniProt Gene Name
HADH [Similar Products]
UniProt Synonym Gene Names
HAD; HADHSC; SCHAD; HCDH [Similar Products]
NCBI Summary for HADH
This gene is a member of the 3-hydroxyacyl-CoA dehydrogenase gene family. The encoded protein functions in the mitochondrial matrix to catalyze the oxidation of straight-chain 3-hydroxyacyl-CoAs as part of the beta-oxidation pathway. Its enzymatic activity is highest with medium-chain-length fatty acids. Mutations in this gene cause one form of familial hyperinsulinemic hypoglycemia. The human genome contains a related pseudogene of this gene on chromosome 15. [provided by RefSeq, May 2010]
UniProt Comments for HADH
Plays an essential role in the mitochondrial beta-oxidation of short chain fatty acids. Exerts it highest activity toward 3-hydroxybutyryl-CoA.
Research Articles on HADH
1. The most frequently seen mutations in Turkish patients with congenital hyperinsulinism (CHI) were ATP binding cassette subfamily C member 8 (ABCC8) gene, followed by 3-hydroxyacyl CoA dehydrogenase (HADH) and kcnj11 channel (KCNJ11) genes.
Precautions
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Disclaimer
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