Full Product Name
ALG11 antibody - C-terminal region
Product Gene Name
anti-ALG11 antibody
[Similar Products]
Product Synonym Gene Name
GT8; KIAA0266; CDG1P[Similar Products]
Antibody/Peptide Pairs
ALG11 peptide (MBS3232350) is used for blocking the activity of ALG11 antibody (MBS3207385)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Synthetic peptide located within the following region: LHTMWNEHFG IGVVECMAAG TIILAHNSGG PKLDIVIPHE GDITGFLAES
3D Structure
ModBase 3D Structure for Q2TAA5
Species Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Homology
Cow: 92%; Dog: 86%; Guinea Pig: 93%; Horse: 100%; Human: 93%; Mouse: 100%; Rabbit: 86%; Rat: 100%; Yeast: 92%; Zebrafish: 91%
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human ALG11
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-ALG11 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ALG11 antibody
This is a rabbit polyclonal antibody against ALG11. It was validated on Western Blot and immunohistochemistry
Target Description: The function remains unknown.
Product Categories/Family for anti-ALG11 antibody
Polyclonal; Membrane Protein; Drugs and Drug Metabolism; Immunohistochemistry; Glycosylation;
Applications Tested/Suitable for anti-ALG11 antibody
Immunohistochemistry (IHC), Western Blot (WB)
Immunohistochemistry (IHC) of anti-ALG11 antibody
Human kidney
NCBI/Uniprot data below describe general gene information for ALG11. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001004127
[Other Products]
NCBI GenBank Nucleotide #
NM_001004127
[Other Products]
UniProt Primary Accession #
Q2TAA5
[Other Products]
UniProt Related Accession #
Q2TAA5[Other Products]
NCBI Official Full Name
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase
NCBI Official Synonym Full Names
ALG11 alpha-1,2-mannosyltransferase
NCBI Official Symbol
ALG11 [Similar Products]
NCBI Official Synonym Symbols
GT8; CDG1P
[Similar Products]
NCBI Protein Information
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase
UniProt Protein Name
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase
UniProt Synonym Protein Names
Asparagine-linked glycosylation protein 11 homolog; Glycolipid 2-alpha-mannosyltransferase
Protein Family
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase
UniProt Gene Name
ALG11 [Similar Products]
UniProt Synonym Gene Names
GT8 [Similar Products]
UniProt Entry Name
ALG11_HUMAN
NCBI Summary for ALG11
This gene encodes a GDP-Man:Man3GlcNAc2-PP-dolichol-alpha1,2-mannosyltransferase which is localized to the cytosolic side of the endoplasmic reticulum (ER) and catalyzes the transfer of the fourth and fifth mannose residue from GDP-mannose (GDP-Man) to Man3GlcNAc2-PP-dolichol and Man4GlcNAc2-PP-dolichol resulting in the production of Man5GlcNAc2-PP-dolichol. Mutations in this gene are associated with congenital disorder of glycosylation type Ip (CDGIP). This gene overlaps but is distinct from the UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast) gene. A pseudogene of the GDP-Man:Man3GlcNAc2-PP-dolichol-alpha1,2-mannosyltransferase has been identified on chromosome 19. [provided by RefSeq, Aug 2010]
Research Articles on ALG11
1. Hence, we concluded that there is different transcriptional control mechanism between mALG11 and hALG11
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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