Product Synonym Names
PSS2; TGASE5; TGASEX; TGM6; TGMX; TGX
Product Gene Name
anti-TGM5 antibody
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for O43548
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Affinity purification
Immunogen
Recombinant protein of human TGM5
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Preparation and Storage
Aliquot and store at-20 degree C. Avoid repeated freeze/thaw cycles.
Other Notes
Small volumes of anti-TGM5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-TGM5 antibody
This gene encodes a member of the transglutaminase family. The encoded protein catalyzes formation of protein cross-links between glutamine and lysine residues, often resulting in stabilization of protein assemblies. This reaction is calcium dependent. Mutations in this gene have been associated with acral peeling skin syndrome.
Applications Tested/Suitable for anti-TGM5 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-TGM5 antibody
WB: 1:500-1:2000
IHC: 1:50-1:200
IF: 1:50-1:100
NCBI/Uniprot data below describe general gene information for TGM5. It may not necessarily be applicable to this product.
NCBI Accession #
NP_004236.1
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NCBI GenBank Nucleotide #
NM_004245.3
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UniProt Primary Accession #
O43548
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UniProt Secondary Accession #
O43549; Q0VF40; Q9UEZ4[Other Products]
UniProt Related Accession #
O43548[Other Products]
NCBI Official Full Name
protein-glutamine gamma-glutamyltransferase 5 isoform 2
NCBI Official Synonym Full Names
transglutaminase 5
NCBI Official Symbol
TGM5 [Similar Products]
NCBI Official Synonym Symbols
TGX; PSS2; TGM6; TGMX; TGASE5; TGASEX
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NCBI Protein Information
protein-glutamine gamma-glutamyltransferase 5
UniProt Protein Name
Protein-glutamine gamma-glutamyltransferase 5
UniProt Synonym Protein Names
Transglutaminase X; TG(X); TGX; TGase X; Transglutaminase-5; TGase-5
Protein Family
Protein-glutamine gamma-glutamyltransferase
UniProt Gene Name
TGM5 [Similar Products]
UniProt Synonym Gene Names
TGMX; TG(X); TGX; TGase X; TGase-5 [Similar Products]
NCBI Summary for TGM5
This gene encodes a member of the transglutaminase family. The encoded protein catalyzes formation of protein cross-links between glutamine and lysine residues, often resulting in stabilization of protein assemblies. This reaction is calcium dependent. Mutations in this gene have been associated with acral peeling skin syndrome. [provided by RefSeq, Oct 2009]
UniProt Comments for TGM5
Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Contributes to the formation of the cornified cell envelope of keratinocytes.
Research Articles on TGM5
1. Acral PSS (APSS) (OMIM 609796), typically non-inflammatory, is confined to distal extremities with localized exfoliation of the epidermis. It is caused by mutations in the TGM5 gene, encoding transglutaminase 5[3] or in the CTSA gene, encoding cystatin A and it is inherited in autosomal recessive pattern
Precautions
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Disclaimer
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